Detailed information of TA system TA169682

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 2435442..2436844
• Replicon: chromosome
• Accession: NZ_CP060008
• Organism: Pseudomonas sp. B11D7D

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HNQ27_RS11165
• Protein ID: WP_179526973.1
• Coordinates: 2435442..2436011 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HNQ27_RS11170
• Protein ID: WP_179572453.1
• Coordinates: 2436017..2436844 (+)
• Length: 276 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HNQ27_RS11155	2430919..2431731	+	813	WP_179572451.1	MerR family transcriptional regulator	-
HNQ27_RS11160	2431748..2435236	-	3489	WP_179572452.1	hybrid sensor histidine kinase/response regulator	-
HNQ27_RS11165	2435442..2436011	+	570	WP_179526973.1	GNAT family N-acetyltransferase	Toxin
HNQ27_RS11170	2436017..2436844	+	828	WP_179572453.1	AraC family transcriptional regulator	Antitoxin
HNQ27_RS11175	2436973..2438304	-	1332	WP_179572454.1	peptidase	-
HNQ27_RS11180	2438495..2439067	+	573	WP_179572455.1	LemA family protein	-
HNQ27_RS11185	2439211..2440116	+	906	WP_179572456.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• AraC-type arabinose-binding/dimerisation domain (17-140)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21506.65 Da
• Isoelectric Point: 7.2799

>T169682 WP_179526973.1 NZ_CP060008:2435442-2436011 [Pseudomonas sp. B11D7D]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADLREQRALPFVIRLGDELVGTTRFA
DFINNLPACEIGWTWLDRNQHGSGLNTTIKYLMLRHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALREAMEAGFNA

Nucleotide

• Length: 570 bp

>T169682 NZ_CP076654:c4333245-4333072 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 276 a.a.
• Molecular weight: 30917.26 Da
• Isoelectric Point: 9.0481

>AT169682 WP_179572453.1 NZ_CP060008:2436017-2436844 [Pseudomonas sp. B11D7D]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGSDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNSQVLGALQELGLAKTGMPSFSFSVLHDPRLHAAFLHLHQLLEHGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLVEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKSGCTAVS
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSGVARM

Nucleotide

• Length: 828 bp

>AT169682 NZ_CP076654:c4333569-4333273 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTAATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GACTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG