169666

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648711..4649072 Replicon chromosome
Accession NZ_CP059999
Organism Xanthomonas citri pv. citri strain B2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag HZS92_RS20035 Protein ID WP_005914328.1
Coordinates 4648711..4648845 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag HZS92_RS20040 Protein ID WP_003486606.1
Coordinates 4648920..4649072 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZS92_RS20015 (HZS92_04235) 4643849..4645540 - 1692 WP_015471463.1 M28 family metallopeptidase -
HZS92_RS20020 (HZS92_04236) 4645732..4646676 - 945 WP_015463704.1 MBL fold metallo-hydrolase -
HZS92_RS20025 (HZS92_04237) 4646805..4648094 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
HZS92_RS20030 (HZS92_04238) 4648275..4648484 - 210 WP_003486601.1 CsbD family protein -
HZS92_RS20035 (HZS92_04239) 4648711..4648845 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
HZS92_RS20040 (HZS92_04240) 4648920..4649072 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
HZS92_RS20045 (HZS92_04241) 4649179..4650102 - 924 WP_005927745.1 arginase -
HZS92_RS20050 (HZS92_04242) 4650423..4650875 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
HZS92_RS20055 (HZS92_04243) 4650939..4651298 + 360 WP_003486613.1 hypothetical protein -
HZS92_RS20060 (HZS92_04244) 4651395..4652312 + 918 WP_011052673.1 hypothetical protein -
HZS92_RS20065 (HZS92_04245) 4652309..4652851 + 543 WP_003486615.1 GTPase -
HZS92_RS20070 (HZS92_04247) 4653289..4653972 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T169666 WP_005914328.1 NZ_CP059999:c4648845-4648711 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T169666 NZ_CP076654:283113-283640 [Escherichia coli]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT169666 WP_003486606.1 NZ_CP059999:c4649072-4648920 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169666 NZ_CP076654:282840-283106 [Escherichia coli]
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAGTCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGGGCTGCGGAAGTGATTGAACAGCATCGGCGGG
TGATCCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCTGGTGAAAAGCTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References