Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2589272..2589828 Replicon chromosome
Accession NZ_CP059987
Organism Protaetiibacter sp. SSC-01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H4J02_RS12185 Protein ID WP_187674827.1
Coordinates 2589553..2589828 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H4J02_RS12180 Protein ID WP_187674826.1
Coordinates 2589272..2589556 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4J02_RS12160 2584421..2584747 + 327 WP_187674822.1 YbjQ family protein -
H4J02_RS12165 2584767..2587217 - 2451 WP_187674823.1 DEAD/DEAH box helicase family protein -
H4J02_RS12170 2587214..2588833 - 1620 WP_187674824.1 site-specific DNA-methyltransferase -
H4J02_RS12175 2589019..2589222 + 204 WP_187674825.1 helix-turn-helix transcriptional regulator -
H4J02_RS12180 2589272..2589556 + 285 WP_187674826.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H4J02_RS12185 2589553..2589828 + 276 WP_187674827.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H4J02_RS12190 2589910..2590854 - 945 WP_187674828.1 transcription termination/antitermination protein NusG -
H4J02_RS12195 2590895..2591176 - 282 WP_187674829.1 preprotein translocase subunit SecE -
H4J02_RS12205 2591522..2592418 - 897 WP_187674830.1 LysR family transcriptional regulator ArgP -
H4J02_RS12210 2592492..2593136 + 645 WP_187674831.1 LysE family transporter -
H4J02_RS12215 2593239..2593892 - 654 WP_187674832.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10526.20 Da        Isoelectric Point: 10.2284

>T169642 WP_187674827.1 NZ_CP059987:2589553-2589828 [Protaetiibacter sp. SSC-01]
VTDESHRVEFAGTAKRDLRGVPPRIVPAIIEFVYGDLARTPRRVGKPLQRELEGLWGARRGPYRIIYEIVDEKLVVLVIH
VDHRADVYRPR

Download         Length: 276 bp

>T169642 NZ_CP076646:3546402-3546620 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10569.87 Da        Isoelectric Point: 4.5370

>AT169642 WP_187674826.1 NZ_CP059987:2589272-2589556 [Protaetiibacter sp. SSC-01]
MQTLPISKVKDKLNDFVDSVAMTHDQVTITKNGSPAAVLIGIDEWESLQETLFWLSRPGVLDDVAEARRELAEGRTSSED
EIRAEFGVPRRQTR

Download         Length: 285 bp

>AT169642 NZ_CP076646:3546002-3546376 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References