Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3390823..3391486 Replicon chromosome
Accession NZ_CP059963
Organism Pectobacterium brasiliense strain IPO:3649 NAK:375

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag H5A23_RS14860 Protein ID WP_119870726.1
Coordinates 3390823..3391167 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag H5A23_RS14865 Protein ID WP_119870727.1
Coordinates 3391169..3391486 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A23_RS14840 3387625..3387933 - 309 WP_014916188.1 hypothetical protein -
H5A23_RS14845 3387973..3388593 - 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
H5A23_RS14850 3388629..3389402 - 774 WP_119870724.1 alpha/beta hydrolase -
H5A23_RS14855 3389570..3390598 + 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
H5A23_RS14860 3390823..3391167 + 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A23_RS14865 3391169..3391486 + 318 WP_119870727.1 helix-turn-helix domain-containing protein Antitoxin
H5A23_RS14870 3391573..3391788 - 216 WP_119870728.1 helix-turn-helix domain-containing protein -
H5A23_RS14875 3392385..3392867 + 483 WP_119870729.1 hypothetical protein -
H5A23_RS14880 3392864..3393211 + 348 WP_119870730.1 TIR domain-containing protein -
H5A23_RS14885 3393372..3394949 - 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T169630 WP_119870726.1 NZ_CP059963:3390823-3391167 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T169630 NZ_CP076646:684780-685076 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT169630 WP_119870727.1 NZ_CP059963:3391169-3391486 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT169630 NZ_CP076646:685078-685473 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References