Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 229218..229745 Replicon chromosome
Accession NZ_CP059963
Organism Pectobacterium brasiliense strain IPO:3649 NAK:375

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A23_RS01085 Protein ID WP_119871082.1
Coordinates 229470..229745 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A23_RS01080 Protein ID WP_119871081.1
Coordinates 229218..229466 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A23_RS01065 224310..225659 + 1350 WP_199679142.1 restriction endonuclease subunit S -
H5A23_RS01070 225656..228904 + 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A23_RS01075 228923..229108 + 186 Protein_201 DUF4942 domain-containing protein -
H5A23_RS01080 229218..229466 + 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A23_RS01085 229470..229745 + 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A23_RS01090 229793..230305 + 513 WP_119871083.1 AAA family ATPase -
H5A23_RS01095 230610..231092 - 483 WP_014913962.1 hypothetical protein -
H5A23_RS01100 231103..231807 - 705 WP_014913963.1 hypothetical protein -
H5A23_RS01105 231830..233365 - 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A23_RS01110 233355..234587 - 1233 WP_119871085.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 213824..231092 17268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169622 WP_119871082.1 NZ_CP059963:229470-229745 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169622 NZ_CP076645:c3148180-3147803 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTACGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCCCGCCGGGCGACAGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169622 WP_119871081.1 NZ_CP059963:229218-229466 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169622 NZ_CP076645:c3148637-3148269 [Escherichia coli]
GTGTCAGACACACTCTCCGGGACAACGCATCCCGATGACAATCATGACCGTCCCTGGTGGGGACTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCAAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References