Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4904592..4905119 Replicon chromosome
Accession NZ_CP059962
Organism Pectobacterium brasiliense strain IPO:3710 NAK:380

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A25_RS21635 Protein ID WP_119871082.1
Coordinates 4904844..4905119 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A25_RS21630 Protein ID WP_119871081.1
Coordinates 4904592..4904840 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A25_RS21615 4899684..4901033 + 1350 WP_199679142.1 restriction endonuclease subunit S -
H5A25_RS21620 4901030..4904278 + 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A25_RS21625 4904297..4904482 + 186 Protein_4222 DUF4942 domain-containing protein -
H5A25_RS21630 4904592..4904840 + 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A25_RS21635 4904844..4905119 + 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A25_RS21640 4905167..4905679 + 513 WP_119871083.1 AAA family ATPase -
H5A25_RS21645 4905984..4906466 - 483 WP_014913962.1 hypothetical protein -
H5A25_RS21650 4906477..4907180 - 704 Protein_4227 hypothetical protein -
H5A25_RS21655 4907203..4908738 - 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A25_RS21660 4908728..4909960 - 1233 WP_119871085.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4889198..4906466 17268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169617 WP_119871082.1 NZ_CP059962:4904844-4905119 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169617 NZ_CP076645:1993743-1993997 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169617 WP_119871081.1 NZ_CP059962:4904592-4904840 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169617 NZ_CP076645:1993495-1993746 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References