169602

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4716881..4717544 Replicon chromosome
Accession NZ_CP059961
Organism Pectobacterium brasiliense strain IPO:4057 NAK:249

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag H5A39_RS20870 Protein ID WP_119870726.1
Coordinates 4716881..4717225 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag H5A39_RS20875 Protein ID WP_119870727.1
Coordinates 4717227..4717544 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A39_RS20850 4713683..4713991 - 309 WP_014916188.1 hypothetical protein -
H5A39_RS20855 4714031..4714651 - 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
H5A39_RS20860 4714687..4715460 - 774 WP_119870724.1 alpha/beta hydrolase -
H5A39_RS20865 4715628..4716656 + 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
H5A39_RS20870 4716881..4717225 + 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A39_RS20875 4717227..4717544 + 318 WP_119870727.1 helix-turn-helix domain-containing protein Antitoxin
H5A39_RS20880 4717631..4717846 - 216 WP_119870728.1 helix-turn-helix domain-containing protein -
H5A39_RS20885 4718443..4718925 + 483 WP_119870729.1 hypothetical protein -
H5A39_RS20890 4718922..4719269 + 348 WP_119870730.1 TIR domain-containing protein -
H5A39_RS20895 4719430..4721007 - 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T169602 WP_119870726.1 NZ_CP059961:4716881-4717225 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T169602 NZ_CP076623:c3334231-3333953 [Morganella morganii]
ATGATCAAATCATTCAAACACAAAGGGCTTAAGCAACTTTTTGAAAACGGTGTTATTTCAGGGATTCCGGCTCAGGATGC
TGTCAGAATTAATGATCGTTTGCAGGCTATTGATTCTGCAACCATGATTGACGATTTAAATATTCATATTTATAAATTAC
ATCCCTTGCGGGGAGATCGGGTGGGTATCTGGTCAATAACAGTGAGAGCCAACTGGCGTATTACATTTGAGTTCAGAAAT
GGTGATGCGTATATTTTAAACTTGGAGGATTATCACTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT169602 WP_119870727.1 NZ_CP059961:4717227-4717544 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT169602 NZ_CP076623:c3333953-3333633 [Morganella morganii]
ATGAAACAAGCTATTGTTTCACATCCCGGTACAATCGTAGCCAATATACTGACTGATCTGGGTGTGGGAGTTCGTCAGTT
TGCCGGAAATATCGGGGTAACACCGGCAACGGTTTCCCGGTTTTTATCAGGTAAAACGGCGCTGACCCCGGCACTGGCGA
TACGGATAGCGGCAGCGTTAGGCAGCAACCCGGCATTCTGGCTGCGCTTACAGGCAAATTATGATTTGCACCGCCTGGAA
AAGGAAATCGATATTTCGGGGATTACGCTGTACGGCGATTCTGAAGAAGATGGTTTTTGTAATAGAGCACCGGATAAATA
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References