169599

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2332918..2333954 Replicon chromosome
Accession NZ_CP059961
Organism Pectobacterium brasiliense strain IPO:4057 NAK:249

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag H5A39_RS10710 Protein ID WP_119871526.1
Coordinates 2333379..2333954 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag H5A39_RS10705 Protein ID WP_119871525.1
Coordinates 2332918..2333379 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A39_RS10685 2327979..2328512 + 534 WP_010282870.1 RNA pyrophosphohydrolase -
H5A39_RS10690 2328525..2330771 + 2247 WP_039283946.1 phosphoenolpyruvate--protein phosphotransferase -
H5A39_RS10695 2330998..2331864 + 867 WP_010286783.1 prolipoprotein diacylglyceryl transferase -
H5A39_RS10700 2331901..2332695 + 795 WP_039312476.1 thymidylate synthase -
H5A39_RS10705 2332918..2333379 + 462 WP_119871525.1 helix-turn-helix domain-containing protein Antitoxin
H5A39_RS10710 2333379..2333954 + 576 WP_119871526.1 PIN domain-containing protein Toxin
H5A39_RS10715 2334134..2334637 + 504 WP_119871527.1 prepilin peptidase-dependent protein -
H5A39_RS10720 2334631..2335257 + 627 WP_119871528.1 prepilin peptidase-dependent protein -
H5A39_RS10725 2335293..2335709 + 417 WP_119871529.1 YgdB family protein -
H5A39_RS10730 2335696..2336091 + 396 WP_014914413.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21493.91 Da        Isoelectric Point: 4.7230

>T169599 WP_119871526.1 NZ_CP059961:2333379-2333954 [Pectobacterium brasiliense]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTVLIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGF
EQLIPALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRALI

Download         Length: 576 bp

>T169599 NZ_CP076619:5221351-5221620 [Xanthomonas arboricola pv. corylina]
GTGGCCGACCTGGACGCGATTGCCGACTACATTGCGCTTGAGGACGCTGCCGCCGCAGCGGCACTGGTGAGACGGGTGTT
TGCGCATGTCGAGCAATTGGCCGAACACCCGGAGAGTGGAAGCCGGCCGCAGGAGCTCAAGCGCTCCCGCTACCGTCAAA
TCGTCGAGCCACCTTGCCGCGTGTTCTACCGTGTGGACGGGCAACGCGTTGTCGTGGTTCACGTGATGCGCTCGGAGCGG
TTACTTCGGAAGAATCGTCTTTCGCGCTGA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17277.78 Da        Isoelectric Point: 6.2253

>AT169599 WP_119871525.1 NZ_CP059961:2332918-2333379 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY

Download         Length: 462 bp

>AT169599 NZ_CP076619:5221076-5221333 [Xanthomonas arboricola pv. corylina]
ATGCGCACAGAACTTGTCACCACGCTCAAGCGGCAGGCCACCGAGCTCCTCGCAGATGTCGAGCGCGACAAGGAGCCGAT
CCTGATCACCCAGCATGGCCTGCCCAGCGCATACCTGGTGGACGTCGCCAGCTATGAACGCATGCAACAGCGCATGGCGA
TCCTCGAAGGAATTGCCCGTGGTGAAATGGCGGTAGCCGAAGGCCGCAGCCTGAGCCACGAGCAAGCCAAACAACGCCTG
GCGCGATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References