Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1529021..1529604 Replicon chromosome
Accession NZ_CP059961
Organism Pectobacterium brasiliense strain IPO:4057 NAK:249

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5A39_RS06900 Protein ID WP_119871112.1
Coordinates 1529299..1529604 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A39_RS06895 Protein ID WP_119871111.1
Coordinates 1529021..1529311 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A39_RS06875 1524155..1525417 - 1263 WP_039282588.1 L-rhamnose isomerase -
H5A39_RS06880 1525414..1526904 - 1491 WP_119871109.1 rhamnulokinase -
H5A39_RS06885 1527241..1528080 + 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
H5A39_RS06890 1528105..1528959 + 855 WP_119871110.1 helix-turn-helix domain-containing protein -
H5A39_RS06895 1529021..1529311 + 291 WP_119871111.1 ribbon-helix-helix protein, CopG family Antitoxin
H5A39_RS06900 1529299..1529604 + 306 WP_119871112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A39_RS06905 1529664..1531373 - 1710 WP_119871113.1 ABC transporter ATP-binding protein -
H5A39_RS06910 1531370..1532236 - 867 WP_010285293.1 ABC transporter permease -
H5A39_RS06915 1532229..1533188 - 960 WP_039279295.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.42 Da        Isoelectric Point: 9.4590

>T169595 WP_119871112.1 NZ_CP059961:1529299-1529604 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T169595 NZ_CP076607:1966205-1966555 [Paenibacillus sophorae]
TTGATCGTAAAACGCGGCGACGTTTTCTTTGCCGATCTTTCGCCGGTAGTTGGTTCCGAGCAGGGCGGAGTAAGGCCTGT
TCTTGTAATTCAGAACGATATTGGCAATCGCTTTAGTCCAACGGTAATTGTTGCGGCAATTACCGCACAGATCCAGAAGG
CCAAACTGCCTACCCATGTGGAAATTGATGCGTCATCCCACGGCTTTGACCGGGATTCCGTCATTCTGCTGGAGCAGGTT
CGGACGATCGACAAGCAGCGCTTGACGGATAAGATCACCCATCTTGACGACGAAACGATGAAAAAGGTGGATGACTCGCT
GCAGATCAGTCTGGGTCTGATTGATTTTTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11100.17 Da        Isoelectric Point: 4.7845

>AT169595 WP_119871111.1 NZ_CP059961:1529021-1529311 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT169595 NZ_CP076607:1965920-1966201 [Paenibacillus sophorae]
TTGGCCAATTTGCATAACACCAAAAGAATCATGATCAGCTTGCCCGATCATCTCTTGCAGGAGGTGGACGGAATTGTCCA
GATGGAGAATTCCAATCGCAGTGAATTGATCCGGCAAGCCATGAAGCTGTATCTCAGCGAACGGAGGAAGCGTTCCATAA
GGGAGTCCATGCAGCGCGGATACATGGAAATGGCCAAGATCAACTTGACCATGGCATGCGAAGCGTTCCTTGCCGAGGAA
GATGCAGACAGCACTCTTGGCCGCTTAGTAAGCGGGGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References