Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1474050..1474577 Replicon chromosome
Accession NZ_CP059961
Organism Pectobacterium brasiliense strain IPO:4057 NAK:249

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A39_RS06680 Protein ID WP_119871082.1
Coordinates 1474302..1474577 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A39_RS06675 Protein ID WP_119871081.1
Coordinates 1474050..1474298 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A39_RS06660 1469142..1470491 + 1350 WP_199679142.1 restriction endonuclease subunit S -
H5A39_RS06665 1470488..1473736 + 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A39_RS06670 1473755..1473940 + 186 Protein_1295 DUF4942 domain-containing protein -
H5A39_RS06675 1474050..1474298 + 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A39_RS06680 1474302..1474577 + 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A39_RS06685 1474625..1475137 + 513 WP_119871083.1 AAA family ATPase -
H5A39_RS06690 1475442..1475924 - 483 WP_014913962.1 hypothetical protein -
H5A39_RS06695 1475935..1476639 - 705 WP_014913963.1 hypothetical protein -
H5A39_RS06700 1476662..1478197 - 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A39_RS06705 1478187..1479419 - 1233 WP_119871085.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1458656..1475924 17268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169594 WP_119871082.1 NZ_CP059961:1474302-1474577 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169594 NZ_CP076606:c42840-42529 [Raoultella ornithinolytica]
ATGCACATTGTATCGAGAGCACCTTTCGATACAGCCACCAGGCAATTCCCCAATCAGGCAGCGGCACTAGACGACGTATA
CCGGACTTTGAAGAGAGAGAACTACACTTCACCGGACGAAATGAAAAAACGATTTGCCTCGCTGGACAGAATGAAATATC
GGGAGAAGTGGTGGGTGATCGATGTTGGCGGTGGGAATTTAAGGGTGATGTTTTTTGCTGATTTTGAACGTGGGAAAATC
TTTATAAAGCACATAACCACACACGCCGAATACGACAAGCTGACAGATTTTTACCGGAGAACTAAAGAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169594 WP_119871081.1 NZ_CP059961:1474050-1474298 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169594 NZ_CP076606:c42532-42113 [Raoultella ornithinolytica]
ATGATGTACACCGATGCTATCCAGGCGGCAAACAGCCTGGTTAGCATTGTCCCCCTCCTGGGGGGCAATGCCTCTCGCAA
GGACTATGAAGACGCGCTGACGCTGGTTGAATACCTGGTTGAACACGAGCCAGATCATCCGCTGGTGGACATGCTGGTTG
CGAAAATTGCCCAGTATGAAGATGAGGCGGAAGAGTTCGCAGAGTTCAACGACCGTATTGCAGCGTTACCAAGTGGCGTG
GCCCTGCTGCGTGTCCTGATGGACCAGCACAAACTGACTCAGAGTGATTTTGAGGAAGAGATTGGTAAGAAATCGCTGGT
GAGCCGCATCCTTAACGGGACTCGCTCACTAACACTAGATCACATGAAAGCACTTGCGCGGCGCTTCAACATTCCGCCCA
GCTCATTCATGGACGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References