169593

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 1379814..1380345 Replicon chromosome
Accession NZ_CP059961
Organism Pectobacterium brasiliense strain IPO:4057 NAK:249

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag H5A39_RS06255 Protein ID WP_039282785.1
Coordinates 1380058..1380345 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag H5A39_RS06250 Protein ID WP_039282788.1
Coordinates 1379814..1380068 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A39_RS06225 1375015..1375605 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
H5A39_RS06230 1375669..1376064 - 396 WP_072036118.1 YraN family protein -
H5A39_RS06235 1376022..1378040 - 2019 WP_039282794.1 penicillin-binding protein activator -
H5A39_RS06240 1378102..1378989 + 888 WP_039556326.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
H5A39_RS06250 1379814..1380068 + 255 WP_039282788.1 plasmid stabilization protein Antitoxin
H5A39_RS06255 1380058..1380345 + 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A39_RS06260 1380543..1381328 + 786 WP_119871053.1 4,5-DOPA dioxygenase extradiol -
H5A39_RS06265 1381396..1382556 - 1161 WP_039462681.1 glutathionylspermidine synthase family protein -
H5A39_RS06270 1382568..1383242 - 675 WP_010280216.1 DUF1190 family protein -
H5A39_RS06275 1383513..1384904 - 1392 WP_039282780.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T169593 WP_039282785.1 NZ_CP059961:1380058-1380345 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T169593 NZ_CP076605:c4712759-4712472 [Raoultella ornithinolytica]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCAGCAAGCAATCTAAGAAAACATGGGATTCGCTTCGAGGAGGCGGT
ACTGGTTTTTGACGATCCGCAGCATCTTTCCCGACATGATCGCTATGAAAATGGTGAGTATCGATGGCAAACCATCGGGC
TTGTTCATGGCGTGATTGTTGTTCTTGTGGCGCATTCGATCCGATTTGAAAGTGGAACGGAGGTCATTCGTATTATCAGC
GCCCGGAAGGCGGACAAAAAAGAGAGGAGTCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT169593 WP_039282788.1 NZ_CP059961:1379814-1380068 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT169593 NZ_CP076605:c4712485-4712180 [Raoultella ornithinolytica]
ATGAGCATGGTTAAACATAAACGCGATAACCCGACAGCGCTTACCGCTCAGCGTGAAGACGAACTCAAAGCGCTGGCGAA
AAAATCAGATGATGACATTGATTACAGCGATATCCCCTCTTCGGACGATGAGCCGTGGTCAGAGGCGGTTCGTGGTAAAT
TTTATCGGCCATTAAAAACGCAGGCCTCTGTGCGCATCGATGCAGATGTGATGGAGTGGCTTAAACGCCCGGGAAAAGGC
TATCAAACGCGGCTGAATGCGATTTTAAGAGAAGCGATGATTCGCGAGCAGAATAAGAAATCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References