Detailed information of TA system TA169577

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1864099..1864682
• Replicon: chromosome
• Accession: NZ_CP059960
• Organism: Pectobacterium brasiliense strain IPO:4060 NAK:251

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: H5A37_RS08425
• Protein ID: WP_119871112.1
• Coordinates: 1864377..1864682 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H5A37_RS08420
• Protein ID: WP_119871111.1
• Coordinates: 1864099..1864389 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H5A37_RS08400	1859233..1860495	-	1263	WP_039282588.1	L-rhamnose isomerase	-
H5A37_RS08405	1860492..1861982	-	1491	WP_119871109.1	rhamnulokinase	-
H5A37_RS08410	1862319..1863158	+	840	WP_014913998.1	HTH-type transcriptional activator RhaS	-
H5A37_RS08415	1863183..1864037	+	855	WP_119871110.1	helix-turn-helix domain-containing protein	-
H5A37_RS08420	1864099..1864389	+	291	WP_119871111.1	ribbon-helix-helix protein, CopG family	Antitoxin
H5A37_RS08425	1864377..1864682	+	306	WP_119871112.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H5A37_RS08430	1864742..1866451	-	1710	WP_119871113.1	ABC transporter ATP-binding protein	-
H5A37_RS08435	1866448..1867314	-	867	WP_010285293.1	ABC transporter permease	-
H5A37_RS08440	1867307..1868266	-	960	WP_039279295.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11602.42 Da
• Isoelectric Point: 9.4590

>T169577 WP_119871112.1 NZ_CP059960:1864377-1864682 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Nucleotide

• Length: 306 bp

>T169577 NZ_CP076596:2315057-2315332 [Erwinia amylovora]
ATGGAAATACAGTGGACCCAAAAGGCCCAGGATGACCTGGAGCGTATTTATAGGTTTGCCTGTCAGTACAGTCGGCAACA
TGCTGACAACGTATTAGAGCGTTTGCTCATAGGAACCTCAGGGCTCGCCGACCATCCAAGAATCGGTGTTTCTCAGATAA
GATATGAACCACGAGAAGTGAGAAAAATCTTGTTTGATGATTATGACGTTCACTATGAAATTCAGCGCGACACTATCTAT
ATTGTTGACCTTTGGCATACCCGAGAGGATCGCTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11100.17 Da
• Isoelectric Point: 4.7845

>AT169577 WP_119871111.1 NZ_CP059960:1864099-1864389 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT169577 NZ_CP076596:2314805-2315053 [Erwinia amylovora]
ATGAGACAACTCGCGAAACAGACGATCAGCGCTCAGATCCCTGCAGAGCTTGCCGCGGCGGTTGAAAACCTGGCTATTGA
ACTGGACAGATCTAAAAGCTGGGTGATTAAAGAAGCGCTGACCGCCATGATTGAAGAGAGAGAGCGGCGGCATCAGCAGA
TTTTGAAAGGGCTTGCTGATGTCGATGCGGGAAGAGTGGTTAGCCATGCGGATGTAGTTGACTTCGCTAACAAACTGAAA
AAATCGTAA