Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1809128..1809655 Replicon chromosome
Accession NZ_CP059960
Organism Pectobacterium brasiliense strain IPO:4060 NAK:251

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A37_RS08205 Protein ID WP_119871082.1
Coordinates 1809380..1809655 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A37_RS08200 Protein ID WP_119871081.1
Coordinates 1809128..1809376 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A37_RS08185 1804220..1805569 + 1350 WP_199679142.1 restriction endonuclease subunit S -
H5A37_RS08190 1805566..1808814 + 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A37_RS08195 1808833..1809018 + 186 Protein_1576 DUF4942 domain-containing protein -
H5A37_RS08200 1809128..1809376 + 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A37_RS08205 1809380..1809655 + 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A37_RS08210 1809703..1810215 + 513 WP_119871083.1 AAA family ATPase -
H5A37_RS08215 1810520..1811002 - 483 WP_014913962.1 hypothetical protein -
H5A37_RS08220 1811013..1811717 - 705 WP_014913963.1 hypothetical protein -
H5A37_RS08225 1811740..1813275 - 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A37_RS08230 1813265..1814497 - 1233 WP_119871085.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1793734..1811002 17268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169576 WP_119871082.1 NZ_CP059960:1809380-1809655 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169576 NZ_CP076596:2313442-2313762 [Erwinia amylovora]
ATGCACATTTCAACTGTACCGGCCACGGTGCCGGTTTCGTCACGCCTGTCTCCCGTGCAGGTGTGGCAGCAACTTTTAAC
GTATCTGCTGGAGCATCATTACGGCTTGACACTAAATGACACGCCATTCCATGACGACGCGGCCATTGAGGAGCATATCG
ACGCAGGAATCACGCTCGCCGATGCTGTTAATTTTCTGGTGGAACGTTATGAACTGGTACGTATCGACCGCAAAGGATTT
ACATGGCAGGAGCAGACGCCATTCCTGGCCGCCACCGATATTCTCAGAGCAAGGCGAGCTACCGGATTAATAAATATTTA
A

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169576 WP_119871081.1 NZ_CP059960:1809128-1809376 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169576 NZ_CP076596:2313082-2313405 [Erwinia amylovora]
ATGTCAATCACACTACCTCATGAATGGGGTCTACAAAGCGATATCACCCCACGATTTGGCGCGAGATTAGTTCAGGAAGG
CAATCGGCTGTATTACCTGGCTGACAGGGCTGGATTAACGGTGAGCTTTAGCCCGATACACCTGCAGAAACTGGATCAGG
CTTTCCCGCTGTTTGTAGAACAACTGGAAAATATGCTGCGTGCTGGCGAACTAAATCCACATCAGCAACATCAGGTGACC
ATTCAACTTACGAGTTTAACCTGTATAGCTGATACCCGTGGTAGCTGCGGTTACGTTTACATTTCTATTTATCCAACCCC
ATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References