Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 446729..447369 | Replicon | chromosome |
Accession | NZ_CP059959 | ||
Organism | Pectobacterium brasiliense strain IPO:4062 NAK:237 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | H5A40_RS02065 | Protein ID | WP_052902920.1 |
Coordinates | 446729..447145 (-) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | H5A40_RS02070 | Protein ID | WP_205591870.1 |
Coordinates | 447142..447369 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H5A40_RS02045 | 442119..443105 | - | 987 | WP_040033638.1 | quinone oxidoreductase | - |
H5A40_RS02050 | 443429..444835 | + | 1407 | WP_010279223.1 | replicative DNA helicase | - |
H5A40_RS02055 | 444877..445959 | + | 1083 | WP_205591869.1 | alanine racemase | - |
H5A40_RS02060 | 445952..446590 | + | 639 | WP_039517591.1 | hypothetical protein | - |
H5A40_RS02065 | 446729..447145 | - | 417 | WP_052902920.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
H5A40_RS02070 | 447142..447369 | - | 228 | WP_205591870.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
H5A40_RS02075 | 448346..448825 | + | 480 | WP_010279234.1 | Lrp/AsnC family transcriptional regulator | - |
H5A40_RS02080 | 449076..449690 | + | 615 | WP_014916569.1 | YitT family protein | - |
H5A40_RS02085 | 449754..450947 | + | 1194 | WP_039465897.1 | aspartate/tyrosine/aromatic aminotransferase | - |
H5A40_RS02090 | 451031..451528 | + | 498 | WP_039278469.1 | M48 family metallopeptidase | - |
H5A40_RS02095 | 451653..452132 | + | 480 | WP_014916572.1 | Hcp family type VI secretion system effector | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 15302.86 Da Isoelectric Point: 8.2931
>T169559 WP_052902920.1 NZ_CP059959:c447145-446729 [Pectobacterium brasiliense]
VSRLFMLDTNICSFIMREHPAEVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIELAAAGTPIGPNDTAIAGHAISVKAILVTNNLREFERVPGLTLEDWVK
VSRLFMLDTNICSFIMREHPAEVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIELAAAGTPIGPNDTAIAGHAISVKAILVTNNLREFERVPGLTLEDWVK
Download Length: 417 bp
>T169559 NZ_CP076592:3694913-3695284 [Erwinia amylovora]
ATGATTTATTTTCTATCCAGTCAAGACATCATCGGCATTCATCAGCGTATGATCGTCGCTTACGGCGGTCTTGCCGGTTA
TGCCGATCCTGGTCGGATAGAAAGTATGGCAACACGGATTCTGAACCGCCACATCTACGAAGGTGAGGATGATATCTATA
TTCTGGCAGCTGCATATCTGCTGGCCATTGCGCGCGGGCATTGTTTCAATGATGCAAATAAGAGAACCGCATTTGCTTCA
ACTGCTTTATTCCTGCGCCGTAATGGCATTCTTCTTCGCTTTTCCCCAATCCATGAACAGCTGACTGTCTCAGCAGCACA
GGGGAGCCTGGATGTGTGGCACATTGCTGAAGCACTGAAACAGTCGACATAA
ATGATTTATTTTCTATCCAGTCAAGACATCATCGGCATTCATCAGCGTATGATCGTCGCTTACGGCGGTCTTGCCGGTTA
TGCCGATCCTGGTCGGATAGAAAGTATGGCAACACGGATTCTGAACCGCCACATCTACGAAGGTGAGGATGATATCTATA
TTCTGGCAGCTGCATATCTGCTGGCCATTGCGCGCGGGCATTGTTTCAATGATGCAAATAAGAGAACCGCATTTGCTTCA
ACTGCTTTATTCCTGCGCCGTAATGGCATTCTTCTTCGCTTTTCCCCAATCCATGAACAGCTGACTGTCTCAGCAGCACA
GGGGAGCCTGGATGTGTGGCACATTGCTGAAGCACTGAAACAGTCGACATAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8878.14 Da Isoelectric Point: 5.8508
>AT169559 WP_205591870.1 NZ_CP059959:c447369-447142 [Pectobacterium brasiliense]
MRIVSVFKNGNNRAIRLPRDMDFEGVNKLEIVREGDTIMLRPVKPNWHSFLQEDRADADFMTERQDVVEEGRFKL
MRIVSVFKNGNNRAIRLPRDMDFEGVNKLEIVREGDTIMLRPVKPNWHSFLQEDRADADFMTERQDVVEEGRFKL
Download Length: 228 bp
>AT169559 NZ_CP076592:3694695-3694916 [Erwinia amylovora]
ATGCAAGCTATAAACTTTACTACCGCCCGTAACGAACTGGCATCAGTTCTTGATAGCGTTGCCAGCGGTGAGCCAGTTAT
GATCACCCGCAGATCGGCCAAATCCGTGGTTGTGGTTGATGCCGCGCAGTATGAAAAAATGCAAAAAATTCAGGCAGAAT
CGGACTTTGATTGGTTGTTTACAGAACATGGCCAGACGCTTGAAGCTCTTAAAAACCGATGA
ATGCAAGCTATAAACTTTACTACCGCCCGTAACGAACTGGCATCAGTTCTTGATAGCGTTGCCAGCGGTGAGCCAGTTAT
GATCACCCGCAGATCGGCCAAATCCGTGGTTGTGGTTGATGCCGCGCAGTATGAAAAAATGCAAAAAATTCAGGCAGAAT
CGGACTTTGATTGGTTGTTTACAGAACATGGCCAGACGCTTGAAGCTCTTAAAAACCGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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