169558

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3763005..3763668 Replicon chromosome
Accession NZ_CP059958
Organism Pectobacterium brasiliense strain IPO:4065 NAK:223

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag H5A29_RS16705 Protein ID WP_119870726.1
Coordinates 3763324..3763668 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag H5A29_RS16700 Protein ID WP_119870727.1
Coordinates 3763005..3763322 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A29_RS16680 3759542..3761119 + 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -
H5A29_RS16685 3761280..3761627 - 348 WP_119870730.1 TIR domain-containing protein -
H5A29_RS16690 3761624..3762106 - 483 WP_119870729.1 hypothetical protein -
H5A29_RS16695 3762703..3762918 + 216 WP_119870728.1 helix-turn-helix domain-containing protein -
H5A29_RS16700 3763005..3763322 - 318 WP_119870727.1 helix-turn-helix domain-containing protein Antitoxin
H5A29_RS16705 3763324..3763668 - 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A29_RS16710 3763893..3764921 - 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
H5A29_RS16715 3765089..3765862 + 774 WP_119870724.1 alpha/beta hydrolase -
H5A29_RS16720 3765898..3766518 + 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
H5A29_RS16725 3766558..3766866 + 309 WP_014916188.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T169558 WP_119870726.1 NZ_CP059958:c3763668-3763324 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T169558 NZ_CP076592:c2939967-2939749 [Erwinia amylovora]
ATGACTGACAAACTTCTAACGAAAACTGACTACCTGATGCGCCTCAGGCGTTGTCGTTCAATCGATACACTTGAACGCGT
GATTGAAAAGAACAAGTACGAATTATCTGATGATGAACTGGCTGTATTTTATTCAGCCGCCGATCACCGTCTTGCTGAAC
TAACCATGAATAAGCTGTACGACAAAGTACCGGTCGCTGTCTGGAAGTTTGTCCGTTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT169558 WP_119870727.1 NZ_CP059958:c3763322-3763005 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT169558 NZ_CP076592:c2940376-2939987 [Erwinia amylovora]
ATGGACGAATACTCACCGAAAAGGCATGATATTGCGCAGCTGAAATTCTTATGTGAAAACCTGTATGATGAAAGTCTGGC
TACGTTAGGCGACAGCCATCATGGCTGGGTTAACGACCCCACCTCAACGAGCAATCTTCAGCTTAACGACCTGATAGAGC
ACATTGCAGCATTCACAATGAATTACAAAATCAAGCATATCGAAGACAGCGATCTGATAAGTCAAATTGATGAGTATCTG
GACGACACCTTTATGCTTTTCAGCAATTACGGTGTCAACAATCTTGACTTACAACGCTGGCAAAAATCAGCGAAGCGATT
GTTTAACATTTTTGCTAAAGAATGCGTAATGAGCCAGATCCAGTCCAGCCATTCATTTAGCAGCCCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References