169549

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 1966633..1967164 Replicon chromosome
Accession NZ_CP059958
Organism Pectobacterium brasiliense strain IPO:4065 NAK:223

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag H5A29_RS08595 Protein ID WP_039282785.1
Coordinates 1966633..1966920 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag H5A29_RS08600 Protein ID WP_039282788.1
Coordinates 1966910..1967164 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A29_RS08575 1962074..1963465 + 1392 WP_039282780.1 outer membrane channel protein TolC -
H5A29_RS08580 1963736..1964410 + 675 WP_010280216.1 DUF1190 family protein -
H5A29_RS08585 1964422..1965582 + 1161 WP_039462681.1 glutathionylspermidine synthase family protein -
H5A29_RS08590 1965650..1966435 - 786 WP_119871053.1 4,5-DOPA dioxygenase extradiol -
H5A29_RS08595 1966633..1966920 - 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A29_RS08600 1966910..1967164 - 255 WP_039282788.1 plasmid stabilization protein Antitoxin
H5A29_RS08610 1967989..1968876 - 888 WP_039556326.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
H5A29_RS08615 1968938..1970956 + 2019 WP_039282794.1 penicillin-binding protein activator -
H5A29_RS08620 1970914..1971309 + 396 WP_072036118.1 YraN family protein -
H5A29_RS08625 1971373..1971963 + 591 WP_005975525.1 DnaA initiator-associating protein DiaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T169549 WP_039282785.1 NZ_CP059958:c1966920-1966633 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T169549 NZ_CP076591:1387859-1388077 [Erwinia amylovora]
ATGACTGACAAACTTCTAACGAAAACTGACTACCTGATGCGCCTCAGGCGTTGTCGTTCAATCGATACACTTGAACGCGT
GATTGAAAAGAACAAGTACGAATTATCTGATGATGAACTGGCTGTATTTTATTCAGCCGCCGATCACCGTCTTGCTGAAC
TAACCATGAATAAGCTGTACGACAAAGTACCGGTCGCTGTCTGGAAGTTTGTCCGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT169549 WP_039282788.1 NZ_CP059958:c1967164-1966910 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT169549 NZ_CP076591:1387450-1387839 [Erwinia amylovora]
ATGGACGAATACTCACCGAAAAGGCATGATATTGCGCAGCTGAAATTCTTATGTGAAAACCTGTATGATGAAAGTCTGGC
TACGTTAGGCGACAGCCATCATGGCTGGGTTAACGACCCCACCTCAACGAGCAATCTTCAGCTTAACGACCTGATAGAGC
ACATTGCAGCATTCACAATGAATTACAAAATCAAGCATATCGAAGACAGCGATCTGATAAGTCAAATTGATGAGTATCTG
GACGACACCTTTATGCTTTTCAGCAATTACGGTGTCAACAATCTTGACTTACAACGCTGGCAAAAATCAGCGAAGCGATT
GTTTAACATTTTTGCTAAAGAATGCGTAATGAGCCAGATCCAGTCCAGCCATTCATTTAGCAGCCCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References