Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1872403..1872930 Replicon chromosome
Accession NZ_CP059958
Organism Pectobacterium brasiliense strain IPO:4065 NAK:223

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A29_RS08170 Protein ID WP_119871082.1
Coordinates 1872403..1872678 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A29_RS08175 Protein ID WP_119871081.1
Coordinates 1872682..1872930 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A29_RS08145 1867561..1868793 + 1233 WP_119871085.1 FtsX-like permease family protein -
H5A29_RS08150 1868783..1870318 + 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A29_RS08155 1870341..1871045 + 705 WP_014913963.1 hypothetical protein -
H5A29_RS08160 1871056..1871538 + 483 WP_014913962.1 hypothetical protein -
H5A29_RS08165 1871843..1872355 - 513 WP_119871083.1 AAA family ATPase -
H5A29_RS08170 1872403..1872678 - 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A29_RS08175 1872682..1872930 - 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A29_RS08180 1873040..1873225 - 186 Protein_1606 DUF4942 domain-containing protein -
H5A29_RS08185 1873244..1876492 - 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A29_RS08190 1876489..1877838 - 1350 WP_199679142.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1871843..1887097 15254


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169548 WP_119871082.1 NZ_CP059958:c1872678-1872403 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169548 NZ_CP076591:c632914-632543 [Erwinia amylovora]
ATGATTTATTTTCTATCCAGTCAAGACATCATCGGCATTCATCAGCGTATGATCGTCGCTTACGGCGGTCTTGCCGGTTA
TGCCGATCCTGGTCGGATAGAAAGTATGGCAACACGGATTCTGAACCGCCACATCTACGAAGGTGAGGATGATATCTATA
TTCTGGCAGCTGCATATCTGCTGGCCATTGCGCGCGGGCATTGTTTCAATGATGCAAATAAGAGAACCGCATTTGCTTCA
ACTGCTTTATTCCTGCGCCGTAATGGCATTCTTCTTCGCTTTTCCCCAATCCATGAACAGCTGACTGTCTCAGCAGCACA
GGGGAGCCTGGATGTGTGGCACATTGCTGAAGCACTGAAACAGTCGACATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169548 WP_119871081.1 NZ_CP059958:c1872930-1872682 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169548 NZ_CP076591:c633132-632911 [Erwinia amylovora]
ATGCAAGCTATAAACTTTACTACCGCCCGTAACGAACTGGCATCAGTTCTTGATAGCGTTGCCAGCGGTGAGCCAGTTAT
GATCACCCGCAGATCGGCCAAATCCGTGGTTGTGGTTGATGCCGCGCAGTATGAAAAAATGCAAAAAATTCAGGCAGAAT
CGGACTTTGATTGGTTGTTTACAGAACATGGCCAGACGCTTGAAGCTCTTAAAAACCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References