Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2051879..2052542 Replicon chromosome
Accession NZ_CP059957
Organism Pectobacterium brasiliense strain IPO:4071 NAK:240

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag H5A30_RS09260 Protein ID WP_119870726.1
Coordinates 2052198..2052542 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag H5A30_RS09255 Protein ID WP_119870727.1
Coordinates 2051879..2052196 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A30_RS09235 2048416..2049993 + 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -
H5A30_RS09240 2050154..2050501 - 348 WP_119870730.1 TIR domain-containing protein -
H5A30_RS09245 2050498..2050980 - 483 WP_119870729.1 hypothetical protein -
H5A30_RS09250 2051577..2051792 + 216 WP_119870728.1 helix-turn-helix domain-containing protein -
H5A30_RS09255 2051879..2052196 - 318 WP_119870727.1 helix-turn-helix domain-containing protein Antitoxin
H5A30_RS09260 2052198..2052542 - 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A30_RS09265 2052767..2053795 - 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
H5A30_RS09270 2053963..2054736 + 774 WP_119870724.1 alpha/beta hydrolase -
H5A30_RS09275 2054772..2055392 + 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
H5A30_RS09280 2055432..2055740 + 309 WP_014916188.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T169536 WP_119870726.1 NZ_CP059957:c2052542-2052198 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T169536 NZ_CP076589:c1206778-1206560 [Erwinia amylovora]
ATGACTGACAAACTTCTAACGAAAACTGACTACCTGATGCGCCTCAGGCGTTGTCGTTCAATCGATACACTTGAACGCGT
GATTGAAAAGAACAAGTACGAATTATCTGATGATGAACTGGCTGTATTTTATTCAGCCGCCGATCACCGTCTTGCTGAAC
TAACCATGAATAAGCTGTACGACAAAGTACCGGTCGCTGTCTGGAAGTTTGTCCGTTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT169536 WP_119870727.1 NZ_CP059957:c2052196-2051879 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT169536 NZ_CP076589:c1207187-1206798 [Erwinia amylovora]
ATGGACGAATACTCACCGAAAAGGCATGATATTGCGCAGCTGAAATTCTTATGTGAAAACCTGTATGATGAAAGTCTGGC
TACGTTAGGCGACAGCCATCATGGCTGGGTTAACGACCCCACCTCAACGAGCAATCTTCAGCTTAACGACCTGATAGAGC
ACATTGCAGCATTCACAATGAATTACAAAATCAAGCATATCGAAGACAGCGATCTGATAAGTCAAATTGATGAGTATCTG
GACGACACCTTTATGCTTTTCAGCAATTACGGTGTCAACAATCTTGACTTACAACGCTGGCAAAAATCAGCGAAGCGATT
GTTTAACATTTTTGCTAAAGAATGCGTAATGAGCCAGATCCAGTCCAGCCATTCATTTAGCAGCCCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References