Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 161268..161795 Replicon chromosome
Accession NZ_CP059957
Organism Pectobacterium brasiliense strain IPO:4071 NAK:240

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A30_RS00740 Protein ID WP_119871082.1
Coordinates 161268..161543 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A30_RS00745 Protein ID WP_119871081.1
Coordinates 161547..161795 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A30_RS00715 156426..157658 + 1233 WP_119871085.1 FtsX-like permease family protein -
H5A30_RS00720 157648..159183 + 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A30_RS00725 159206..159910 + 705 WP_014913963.1 hypothetical protein -
H5A30_RS00730 159921..160403 + 483 WP_014913962.1 hypothetical protein -
H5A30_RS00735 160708..161220 - 513 WP_119871083.1 AAA family ATPase -
H5A30_RS00740 161268..161543 - 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A30_RS00745 161547..161795 - 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A30_RS00750 161905..162090 - 186 Protein_148 DUF4942 domain-containing protein -
H5A30_RS00755 162109..165357 - 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A30_RS00760 165354..166703 - 1350 WP_199679142.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 160708..175961 15253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169526 WP_119871082.1 NZ_CP059957:c161543-161268 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169526 NZ_CP076547:c2995765-2995328 [Subtercola sp. PAMC28395]
GTGATTCCACAGCCACGTTACGCGCTCGACACAAGTGTCTCTGTGCCGCTCCTGATGAAGGCACACGACGCTCACGACGT
CGTCTCTGCGTGGGCCGCTGGCCGAGTGCTTGGACTCAGTGGACACGCACTCGTCGAGACCTACTCGGTTCTGACTCGCC
TCCCGGGAGATTCTCGGGTCGATTCCGCTGACGCCGTATTGCTCATAGACGACAACTTCCCCGCCCATTTCGCGCTCTCC
GCAGAAGCCACGAGCACGTCTCATCGCGAACTCGCGCGGCACGGCGTTTCAGGTGGAGCAACATACGACGGTCTCGTCGC
CCTGGCGGCCCGGGAACACGAAGCGGTGTTGGTGACGCGTGACGCGCGGGCCAGACAGACCTATGAGGCCCTGGGCGTCA
AGGTGGAGATCATCACCGTCCCGAGCGTGTCACGGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169526 WP_119871081.1 NZ_CP059957:c161795-161547 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169526 NZ_CP076547:c2996001-2995762 [Subtercola sp. PAMC28395]
ATGGAAGCGACGATTGACTCTGGCGGCAGACTCCTTCTACCGAAGAGCCTTCGTGATGCATTGGGTCTTGGCCCGGGTTC
GAAAGTAGACGTGTCGGCCTATGGTGGAGGGCTGCAGGTGACGCCGGGCGGGCGGACTGCGCGCTTGGAGCGGGGTGAAG
ATGGGCGTCTGGTGGCAAGTTCAGAGACATCTGTCTCAGACGACGTTCTGTTCGCACTGATCGATTCTGGGCGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References