Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4732329..4732864 Replicon chromosome
Accession NZ_CP059956
Organism Pectobacterium brasiliense strain IPO:4132 NAK:239

Toxin (Protein)


Gene name relE Uniprot ID A0A7V8Q6Q4
Locus tag H5A38_RS21125 Protein ID WP_039284929.1
Coordinates 4732577..4732864 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag H5A38_RS21120 Protein ID WP_010281712.1
Coordinates 4732329..4732580 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A38_RS21095 4727961..4728473 - 513 WP_164669160.1 phenolic acid decarboxylase -
H5A38_RS21100 4728573..4729445 + 873 WP_205533918.1 LysR family transcriptional regulator -
H5A38_RS21105 4729489..4730112 - 624 WP_205557443.1 LysE family transporter -
H5A38_RS21110 4730380..4731135 + 756 WP_039284933.1 thiol:disulfide interchange protein DsbG -
H5A38_RS21115 4731169..4732074 - 906 WP_039284931.1 siderophore-interacting protein -
H5A38_RS21120 4732329..4732580 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H5A38_RS21125 4732577..4732864 + 288 WP_039284929.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A38_RS21130 4732984..4734336 - 1353 WP_010296544.1 glutathione-disulfide reductase -
H5A38_RS21135 4734465..4735307 - 843 WP_010281707.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
H5A38_RS21140 4735588..4735971 - 384 WP_205557445.1 TfoX/Sxy family protein -
H5A38_RS21145 4736071..4737426 - 1356 WP_205547219.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11088.18 Da        Isoelectric Point: 10.3527

>T169522 WP_039284929.1 NZ_CP059956:4732577-4732864 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T169522 NZ_CP076539:238778-239128 [Bacillus thuringiensis]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCAACGGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTATGGTTTTGAGAGAGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTAGATGAAGTGATGATGAGTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT169522 WP_010281712.1 NZ_CP059956:4732329-4732580 [Pectobacterium brasiliense]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT169522 NZ_CP076539:238486-238773 [Bacillus thuringiensis]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAATTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTATATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCG
GAGTATGAAGCAGCTCATACAGTAGAACGCTTAGTTAGCGGGGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8Q6Q4

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References