Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4290782..4291365 Replicon chromosome
Accession NZ_CP059956
Organism Pectobacterium brasiliense strain IPO:4132 NAK:239

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5A38_RS19085 Protein ID WP_205547433.1
Coordinates 4290782..4291087 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A38_RS19090 Protein ID WP_039524406.1
Coordinates 4291075..4291365 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A38_RS19070 4287198..4288157 + 960 WP_039282569.1 ABC transporter permease -
H5A38_RS19075 4288150..4289016 + 867 WP_010285293.1 ABC transporter permease -
H5A38_RS19080 4289013..4290722 + 1710 WP_205547435.1 dipeptide ABC transporter ATP-binding protein -
H5A38_RS19085 4290782..4291087 - 306 WP_205547433.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A38_RS19090 4291075..4291365 - 291 WP_039524406.1 ribbon-helix-helix protein, CopG family Antitoxin
H5A38_RS19095 4291427..4292281 - 855 WP_205547431.1 helix-turn-helix domain-containing protein -
H5A38_RS19100 4292306..4293145 - 840 WP_010285287.1 HTH-type transcriptional activator RhaS -
H5A38_RS19105 4293482..4294972 + 1491 WP_205547429.1 rhamnulokinase -
H5A38_RS19110 4294969..4296231 + 1263 WP_010285282.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11581.43 Da        Isoelectric Point: 8.0458

>T169521 WP_205547433.1 NZ_CP059956:c4291087-4290782 [Pectobacterium brasiliense]
MPQVIVSECARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T169521 NZ_CP076534:1311570-1311839 [Xanthomonas arboricola pv. corylina]
GTGGCCGACCTGGACGCGATTGCCGACTACATTGCGCTTGAGGACGCTGCCGCCGCAGCGGCACTGGTGAGACGGGTGTT
TGCGCATGTCGAGCAATTGGCCGAACACCCGGAGAGTGGAAGCCGGCCGCAGGAGCTCAAGCGCTCCCGCTACCGTCAAA
TCGTCGAGCCACCTTGCCGCGTGTTCTACCGTGTGGACGGGCAACGCGTTGTCGTGGTTCACGTGATGCGCTCGGAGCGG
TTACTTCGGAAGAATCGTCTTTCGCGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11070.14 Da        Isoelectric Point: 4.7845

>AT169521 WP_039524406.1 NZ_CP059956:c4291365-4291075 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT169521 NZ_CP076534:1311295-1311552 [Xanthomonas arboricola pv. corylina]
ATGCGCACAGAACTTGTCACCACGCTCAAGCGGCAGGCCACCGAGCTCCTCGCAGATGTCGAGCGCGACAAGGAGCCGAT
CCTGATCACCCAGCATGGCCTGCCCAGCGCATACCTGGTGGACGTCGCCAGCTATGAACGCATGCAACAGCGCATGGCGA
TCCTCGAAGGAATTGCCCGTGGTGAAATGGCGGTAGCCGAAGGCCGCAGCCTGAGCCACGAGCAAGCCAAACAACGCCTG
GCGCGATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References