Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4214933..4216631 Replicon chromosome
Accession NZ_CP059956
Organism Pectobacterium brasiliense strain IPO:4132 NAK:239

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag H5A38_RS18720 Protein ID WP_205547487.1
Coordinates 4215702..4216631 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag H5A38_RS18715 Protein ID WP_205547489.1
Coordinates 4214933..4215715 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A38_RS18680 4210112..4211413 + 1302 WP_010286407.1 anaerobic C4-dicarboxylate transporter -
H5A38_RS18685 4211545..4211877 + 333 WP_010286405.1 divalent cation tolerance protein CutA -
H5A38_RS18690 4211853..4213583 + 1731 WP_205547491.1 protein-disulfide reductase DsbD -
H5A38_RS18695 4213618..4214193 + 576 WP_014914059.1 transcriptional regulator -
H5A38_RS18705 4214515..4214622 - 108 Protein_3656 helix-turn-helix domain-containing protein -
H5A38_RS18710 4214619..4214756 - 138 WP_172644752.1 hypothetical protein -
H5A38_RS18715 4214933..4215715 + 783 WP_205547489.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
H5A38_RS18720 4215702..4216631 + 930 WP_205547487.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
H5A38_RS18725 4217013..4217915 - 903 WP_205547485.1 LysR family transcriptional regulator -
H5A38_RS18730 4218044..4218307 + 264 WP_012773200.1 DUF2798 domain-containing protein -
H5A38_RS18735 4218383..4219168 - 786 WP_205547483.1 phosphonate metabolism protein PhnP -
H5A38_RS18740 4219207..4219776 - 570 WP_043901802.1 ribose 1,5-bisphosphokinase -
H5A38_RS18745 4219779..4220915 - 1137 WP_205547481.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35039.36 Da        Isoelectric Point: 5.6297

>T169520 WP_205547487.1 NZ_CP059956:4215702-4216631 [Pectobacterium brasiliense]
MDQRDIYVQQVKLLMTALPYVAKQPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGITAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQHNLSALHAKNPAKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T169520 NZ_CP076534:c1173249-1172968 [Xanthomonas arboricola pv. corylina]
ATGATCAGGAGCTTTGTCGACAAGGAAGCCGAAAAGATCTGGATGGGTGAGCGCTCCCGCCGGTTGCCGGCCGACATCCA
GTCGGTCGCGCGCCGCAAGTTGCGCATGCTCAACGCTGCCGCGCACCTCGACGATCTGCGCATTCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCGAGCGGCGCGGGCAGTACAGCATCCGGATCAACGACCAGTGGCGCATCTGCTTCCGATGGATG
GAGGGCGATGTCGCCGAGGTCGAAATTGTTGATTACCACTGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29517.88 Da        Isoelectric Point: 9.2869

>AT169520 WP_205547489.1 NZ_CP059956:4214933-4215715 [Pectobacterium brasiliense]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSMPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSERVEDGSA

Download         Length: 783 bp

>AT169520 NZ_CP076534:c1172950-1172660 [Xanthomonas arboricola pv. corylina]
ATGACAGTCCTACCCAACATCCACCCTGGCGAAATCCTGCGCGAAGAGTTCCTCGAGCCGATGGGCATCAGCCAGAACGC
GCTGGCGCGGGCCACCGGCGTACCGCCGCGTCGCATCAACGAGATCGTCCTGGGCAAGCGCGGCATCACCGCCGACACCG
CCGTGCGCCTGGCTGCAGCGCTGGGCACGACCGAGCGCTTCTGGCTGAGCCTGCAAGCCGATTACGAGCTGGAACAGGCA
CACCGCGCGCTGGGCGATCTGCCGTCGCGGATCAAGCGGCTGGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References