169519

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4051439..4052099 Replicon chromosome
Accession NZ_CP059956
Organism Pectobacterium brasiliense strain IPO:4132 NAK:239

Toxin (Protein)


Gene name cptA Uniprot ID A0A837DIN4
Locus tag H5A38_RS17950 Protein ID WP_039275532.1
Coordinates 4051439..4051852 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag H5A38_RS17955 Protein ID WP_005971623.1
Coordinates 4051833..4052099 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A38_RS17925 4047236..4048564 + 1329 WP_039282120.1 MHS family MFS transporter -
H5A38_RS17930 4048769..4049155 + 387 WP_039282122.1 thioesterase family protein -
H5A38_RS17935 4049499..4050017 + 519 WP_014914178.1 flavodoxin FldB -
H5A38_RS17940 4050046..4050369 + 324 WP_205547559.1 hypothetical protein -
H5A38_RS17945 4050435..4051370 - 936 WP_010301818.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
H5A38_RS17950 4051439..4051852 - 414 WP_039275532.1 protein YgfX Toxin
H5A38_RS17955 4051833..4052099 - 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
H5A38_RS17960 4052335..4053336 + 1002 WP_205536853.1 tRNA-modifying protein YgfZ -
H5A38_RS17965 4053527..4054174 - 648 WP_010279833.1 hemolysin III family protein -
H5A38_RS17970 4054604..4055212 + 609 WP_014914174.1 HD domain-containing protein -
H5A38_RS17975 4055267..4056271 + 1005 WP_205547558.1 substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16311.26 Da        Isoelectric Point: 10.7911

>T169519 WP_039275532.1 NZ_CP059956:c4051852-4051439 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T169519 NZ_CP076534:c840988-840836 [Xanthomonas arboricola pv. corylina]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
TGGCAAGGACATGCAGGGTGCAGGTGAGAAGGTCGAAAAGAAGGCCGACAATTGCAGCGACGGTAAGTGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT169519 WP_005971623.1 NZ_CP059956:c4052099-4051833 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT169519 NZ_CP076534:c840753-840619 [Xanthomonas arboricola pv. corylina]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGGTGTTGTCGGTCGGTATGCTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCTGCGCGCAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DIN4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References