Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4973325..4973988 Replicon chromosome
Accession NZ_CP059955
Organism Pectobacterium brasiliense strain IPO:4134 NAK:395

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag H5A16_RS21960 Protein ID WP_119870726.1
Coordinates 4973325..4973669 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag H5A16_RS21965 Protein ID WP_119870727.1
Coordinates 4973671..4973988 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A16_RS21940 4970127..4970435 - 309 WP_014916188.1 hypothetical protein -
H5A16_RS21945 4970475..4971095 - 621 WP_119870723.1 FMN-dependent NADH-azoreductase -
H5A16_RS21950 4971131..4971904 - 774 WP_119870724.1 alpha/beta hydrolase -
H5A16_RS21955 4972072..4973100 + 1029 WP_119870725.1 helix-turn-helix domain-containing protein -
H5A16_RS21960 4973325..4973669 + 345 WP_119870726.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A16_RS21965 4973671..4973988 + 318 WP_119870727.1 helix-turn-helix domain-containing protein Antitoxin
H5A16_RS21970 4974075..4974290 - 216 WP_119870728.1 helix-turn-helix domain-containing protein -
H5A16_RS21975 4974887..4975369 + 483 WP_119870729.1 hypothetical protein -
H5A16_RS21980 4975366..4975713 + 348 WP_119870730.1 TIR domain-containing protein -
H5A16_RS21985 4975874..4977451 - 1578 WP_014916196.1 glutamine-hydrolyzing GMP synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12393.08 Da        Isoelectric Point: 9.7825

>T169512 WP_119870726.1 NZ_CP059955:4973325-4973669 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
TFQKKSSSGIATPKSDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T169512 NZ_CP076528:c55508-55128 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
TGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGCGCTGCGACTGG
CGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11419.48 Da        Isoelectric Point: 10.6133

>AT169512 WP_119870727.1 NZ_CP059955:4973671-4973988 [Pectobacterium brasiliense]
MSLDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT169512 NZ_CP076528:c55729-55508 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGTGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References