169509

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2589359..2590395 Replicon chromosome
Accession NZ_CP059955
Organism Pectobacterium brasiliense strain IPO:4134 NAK:395

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag H5A16_RS11805 Protein ID WP_119871526.1
Coordinates 2589820..2590395 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag H5A16_RS11800 Protein ID WP_119871525.1
Coordinates 2589359..2589820 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A16_RS11780 2584420..2584953 + 534 WP_010282870.1 RNA pyrophosphohydrolase -
H5A16_RS11785 2584966..2587212 + 2247 WP_039283946.1 phosphoenolpyruvate--protein phosphotransferase -
H5A16_RS11790 2587439..2588305 + 867 WP_010286783.1 prolipoprotein diacylglyceryl transferase -
H5A16_RS11795 2588342..2589136 + 795 WP_039312476.1 thymidylate synthase -
H5A16_RS11800 2589359..2589820 + 462 WP_119871525.1 helix-turn-helix domain-containing protein Antitoxin
H5A16_RS11805 2589820..2590395 + 576 WP_119871526.1 PIN domain-containing protein Toxin
H5A16_RS11810 2590575..2591078 + 504 WP_119871527.1 prepilin peptidase-dependent protein -
H5A16_RS11815 2591072..2591698 + 627 WP_119871528.1 prepilin peptidase-dependent protein -
H5A16_RS11820 2591734..2592150 + 417 WP_119871529.1 YgdB family protein -
H5A16_RS11825 2592137..2592532 + 396 WP_014914413.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21493.91 Da        Isoelectric Point: 4.7230

>T169509 WP_119871526.1 NZ_CP059955:2589820-2590395 [Pectobacterium brasiliense]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTVLIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGF
EQLIPALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRALI

Download         Length: 576 bp

>T169509 NZ_CP076527:4023282-4023617 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17277.78 Da        Isoelectric Point: 6.2253

>AT169509 WP_119871525.1 NZ_CP059955:2589359-2589820 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY

Download         Length: 462 bp

>AT169509 NZ_CP076527:4023034-4023282 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References