Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1811693..1812220 Replicon chromosome
Accession NZ_CP059955
Organism Pectobacterium brasiliense strain IPO:4134 NAK:395

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H5A16_RS08205 Protein ID WP_119871082.1
Coordinates 1811945..1812220 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A16_RS08200 Protein ID WP_119871081.1
Coordinates 1811693..1811941 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A16_RS08185 1806785..1808134 + 1350 WP_199679142.1 restriction endonuclease subunit S -
H5A16_RS08190 1808131..1811379 + 3249 WP_119871080.1 type I restriction endonuclease subunit R -
H5A16_RS08195 1811398..1811583 + 186 Protein_1576 DUF4942 domain-containing protein -
H5A16_RS08200 1811693..1811941 + 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
H5A16_RS08205 1811945..1812220 + 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A16_RS08210 1812268..1812780 + 513 WP_119871083.1 AAA family ATPase -
H5A16_RS08215 1813085..1813567 - 483 WP_014913962.1 hypothetical protein -
H5A16_RS08220 1813578..1814282 - 705 WP_014913963.1 hypothetical protein -
H5A16_RS08225 1814305..1815840 - 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
H5A16_RS08230 1815830..1817062 - 1233 WP_119871085.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1796299..1813567 17268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T169504 WP_119871082.1 NZ_CP059955:1811945-1812220 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T169504 NZ_CP076527:3296002-3296232 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT169504 WP_119871081.1 NZ_CP059955:1811693-1811941 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT169504 NZ_CP076527:3296229-3296588 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References