169501

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1406630..1407165 Replicon chromosome
Accession NZ_CP059955
Organism Pectobacterium brasiliense strain IPO:4134 NAK:395

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag H5A16_RS06310 Protein ID WP_015842269.1
Coordinates 1406630..1406917 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag H5A16_RS06315 Protein ID WP_010281712.1
Coordinates 1406914..1407165 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A16_RS06285 1401942..1402670 - 729 WP_039498362.1 DUF1266 domain-containing protein -
H5A16_RS06290 1402843..1403403 + 561 Protein_1210 alkyl/aryl-sulfatase -
H5A16_RS06295 1403525..1403908 + 384 WP_014913665.1 TfoX/Sxy family protein -
H5A16_RS06300 1404189..1405031 + 843 WP_010281707.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
H5A16_RS06305 1405160..1406512 + 1353 WP_119871553.1 glutathione-disulfide reductase -
H5A16_RS06310 1406630..1406917 - 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A16_RS06315 1406914..1407165 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H5A16_RS06320 1407420..1408325 + 906 WP_119871554.1 siderophore-interacting protein -
H5A16_RS06325 1408359..1409114 - 756 WP_119871555.1 thiol:disulfide interchange protein DsbG -
H5A16_RS06330 1409382..1410005 + 624 WP_119871556.1 LysE family translocator -
H5A16_RS06335 1410065..1411105 - 1041 WP_119871557.1 HipA domain-containing protein -
H5A16_RS06340 1411102..1411416 - 315 WP_039279922.1 HipA N-terminal domain-containing protein -
H5A16_RS06345 1411401..1411727 - 327 WP_039510297.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T169501 WP_015842269.1 NZ_CP059955:c1406917-1406630 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T169501 NZ_CP076527:1742211-1742429 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTTTGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT169501 WP_010281712.1 NZ_CP059955:c1407165-1406914 [Pectobacterium brasiliense]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT169501 NZ_CP076527:1741811-1742185 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References