Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2044240..2044511 Replicon chromosome
Accession NZ_CP059947
Organism Escherichia coli strain 268.2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2044370..2044473 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2044240..2044511 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5C70_RS09755 2040795..2041457 - 663 WP_000944256.1 exodeoxyribonuclease X -
H5C70_RS09760 2041481..2042137 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
H5C70_RS09765 2042239..2042469 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H5C70_RS09770 2042608..2042982 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H5C70_RS09775 2042986..2043858 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
H5C70_RS09780 2043871..2044212 + 342 WP_000976472.1 YebY family protein -
- 2044240..2044511 - 272 - - Antitoxin
- 2044370..2044473 + 104 - - Toxin
H5C70_RS09785 2044608..2045264 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H5C70_RS09790 2045265..2045456 - 192 WP_001296140.1 YebW family protein -
H5C70_RS09795 2045561..2045797 - 237 WP_001295499.1 DUF1480 family protein -
H5C70_RS09800 2045915..2047354 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169463 NZ_CP059947:2044370-2044473 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169463 NZ_CP059947:c2044511-2044240 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References