Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2378122..2378780 Replicon chromosome
Accession NZ_CP059901
Organism Mumia sp. ZJ1417

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H4N58_RS11615 Protein ID WP_167003237.1
Coordinates 2378352..2378780 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H4N58_RS11610 Protein ID WP_167003234.1
Coordinates 2378122..2378355 (+) Length 78 a.a.

Genomic Context

H4N58_RS11585H4N58_RS11605H4N58_RS11610H4N58_RS11615H4N58_RS11620H4N58_RS11590H4N58_RS11595H4N58_RS11600
Location: 2373406..2373561 (156 bp)
Type: Others
Protein ID: WP_167003224.1
Location: 2377138..2378103 (966 bp)
Type: Others
Protein ID: WP_167250634.1
Location: 2378122..2378355 (234 bp)
Type: Antitoxin
Protein ID: WP_167003234.1
Location: 2378352..2378780 (429 bp)
Type: Toxin
Protein ID: WP_167003237.1
Location: 2378888..2381971 (3084 bp)
Type: Others
Protein ID: WP_167250632.1
Location: 2373588..2374337 (750 bp)
Type: Others
Protein ID: WP_167250636.1
Location: 2374347..2375777 (1431 bp)
Type: Others
Protein ID: WP_167003228.1
Location: 2375893..2376996 (1104 bp)
Type: Others
Protein ID: WP_167003230.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H4N58_RS115852373406..2373561+156WP_167003224.1hypothetical protein-
H4N58_RS115902373588..2374337-750WP_167250636.1hypothetical protein-
H4N58_RS115952374347..2375777-1431WP_167003228.1MFS transporter-
H4N58_RS116002375893..2376996-1104WP_167003230.1NAD(P)H-binding protein-
H4N58_RS116052377138..2378103+966WP_167250634.1hypothetical protein-
H4N58_RS116102378122..2378355+234WP_167003234.1ribbon-helix-helix domain-containing proteinAntitoxin
H4N58_RS116152378352..2378780+429WP_167003237.1PIN domain-containing proteinToxin
H4N58_RS116202378888..2381971+3084WP_167250632.1Ig-like domain repeat protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15826.01 Da        Isoelectric Point: 6.8382

>T169327 WP_167003237.1 NZ_CP059901:2378352-2378780 [Mumia sp. ZJ1417]
VRALLDVNVLLALFDRDHADHARARDWLTAEITQGWASCPLTQNGFVRVVGQPQYPSPVPVAQAIQMLARACSTEHHEFW
PSDRSLLDETFVDPRRIHGPRQVTDLYLLATAVAHRGRFVTFDRAIPVSAVPGATNDHLVVL

Download         Length: 429 bp

>T169327 NZ_CP076404:2724144-2724473 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8535.56 Da        Isoelectric Point: 4.6558

>AT169327 WP_167003234.1 NZ_CP059901:2378122-2378355 [Mumia sp. ZJ1417]
VRTTLDIDDDVLRAVKERARREGRSAGAVVSDLVRESLTRSVDMKPDEGFFGFSPLPHRGPVVSNALVDELREEIGE

Download         Length: 234 bp

>AT169327 NZ_CP076404:2723806-2724123 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References