Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 658856..659394 Replicon chromosome
Accession NZ_CP059901
Organism Mumia sp. ZJ1417

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag H4N58_RS03110 Protein ID WP_167001488.1
Coordinates 659092..659394 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag H4N58_RS03105 Protein ID WP_167001487.1
Coordinates 658856..659092 (+) Length 79 a.a.

Genomic Context

H4N58_RS03105H4N58_RS03110H4N58_RS03095H4N58_RS03100H4N58_RS03115H4N58_RS03120H4N58_RS03125
Location: 658856..659092 (237 bp)
Type: Antitoxin
Protein ID: WP_167001487.1
Location: 659092..659394 (303 bp)
Type: Toxin
Protein ID: WP_167001488.1
Location: 656780..657826 (1047 bp)
Type: Others
Protein ID: WP_167001486.1
Location: 657823..658632 (810 bp)
Type: Others
Protein ID: WP_182397175.1
Location: 659767..660492 (726 bp)
Type: Others
Protein ID: WP_167001489.1
Location: 660489..661262 (774 bp)
Type: Others
Protein ID: WP_167001490.1
Location: 661249..663198 (1950 bp)
Type: Others
Protein ID: WP_167249066.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H4N58_RS03095656780..657826-1047WP_167001486.1ornithine cyclodeaminase-
H4N58_RS03100657823..658632-810WP_182397175.1amidinotransferase-
H4N58_RS03105658856..659092+237WP_167001487.1ribbon-helix-helix protein, CopG familyAntitoxin
H4N58_RS03110659092..659394+303WP_167001488.1type II toxin-antitoxin system PemK/MazF family toxinToxin
H4N58_RS03115659767..660492-726WP_167001489.1ABC transporter ATP-binding protein-
H4N58_RS03120660489..661262-774WP_167001490.1ABC transporter ATP-binding protein-
H4N58_RS03125661249..663198-1950WP_167249066.1ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10877.58 Da        Isoelectric Point: 5.6546

>T169326 WP_167001488.1 NZ_CP059901:659092-659394 [Mumia sp. ZJ1417]
MRPIHMARLDKARPVLILTREAVRPYLTRVTVAPITSTIRGLSTEVEVGPVNGLDHVSVVSCDNIVTVPVASVGRQLGFL
LDSQEAELADAVRAAFDLDW

Download         Length: 303 bp

>T169326 NZ_CP076404:2712609-2713682 [Escherichia coli]
ATGACAATCAGGAGTTACAAAAACTTAAATCTGGTCAGGGCAAATATCGAGACTGAATCCAGACAATTCATTGAAAATAA
AAACTATTCAATCCAATCAATTGGTCCTATGCCAGGGTCAAGGGCTGGGCTTCGGGTCGTATTTACCAGACCAGGGGTTA
ACTTGGCAACTGTGGACATTTTTTATAACGGGGACGGTTCGACTACAATTCAATATCTCACTGGAGCCAATCGTTCTCTG
GGCCAAGAGTTAGCGGATCATCTTTTTGAAACCATCAATCCTGCTGAATTTGAGCAGGTAAATATGGTACTGCAAGGATT
TGTAGAGACAAGCGTTCTACCTGTACTTGAGCTATCAGCAGATGAATCGCATATAGAGTTCAGAGAACACTCTCGTAACG
CTCATACCGTAGTGTGGAAAATTATTTCCACCAGCTATCAGGACGAATTGACTGTGAGCCTGCATATCACAACAGGTAAG
CTCCAGATTCAGGGCCGACCGCTGTCATGTTACAGAGTTTTCACGTTTAACTTGGCAGCCCTGCTTGATTTACAGGGTTT
GGAGAAAGTGCTAATCCGCCAGGAGGATGGTAAAGCTAATATTGTTCAACAGGAGGTTGCCCGCACTTACTTGCAGACTG
TAATGGCCGATGCTTACCCGCATCTCCACGTGACTGCCGAAAAATTGCTCGTTTCAGGGCTATGTGTTAAACTCGCCGCC
CCTGATTTGCCTGACTACTGTATGTTACTTTATCCTGAACTACGCACCATTGAAGGTGTCTTAAAAAGTAAGATGAGTGG
GTTAGGCATGCCAGTACAGCAGCCGGCAGGTTTTGGAACTTACTTTGATAAACCTGCTGCTCATTACATTCTGAAACCGC
AATTTGCAGCTACTCTTAGACCGGAACAGATTAACATCATCAGCACAGCCTATACTTTTTTTAATGTGGAACGTCATTCT
CTGTTCCACATGGAAACTGTGGTCGATGCCAGCCGTATGATTTCTGATATGGCCCGGTTGATGGGTAAAGCCACTAGAGC
GTGGGGAATAATCAAGGACTTATATATTGTTTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8689.76 Da        Isoelectric Point: 4.4247

>AT169326 WP_167001487.1 NZ_CP059901:658856-659092 [Mumia sp. ZJ1417]
MSTQIAVRLDEELVEFVDALVRRGEASSRAAVVARALERERRRKTAERDAAILAAARTDADMDDLAEFASRLPMDDID

Download         Length: 237 bp

>AT169326 NZ_CP076404:2713675-2714046 [Escherichia coli]
TTGTTTGAAATCACCGGAATTAACGTCTCAGGGGCTCTAAAAGCTGTCGTTATGGCGACCGGCTTCGAGAACCCTTTGTC
CTCAGTTAATGAAATTGAGACGAAACTTTCTGCCCTACTGGGTAGTGAGACCACTGGTGAAATCCTTTTTGACCTCTTGT
GCGCTAACGGTCCAGAGTGGAACCGCTTCGTTACGCTGGAAATGAAATATGGCCGGATCATGCTGGATACGGCCAAAATT
ATTGATGAGCAGGACGTTCCGACACATATCCTGAGCAAACTGACTTTTACTTTACGTAATCATCCTGAGTACCTAGAAGC
CTCTGTTTTGTCTCCCGATGATGTACGCCAAGTCCTGTCAATGGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References