Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 168801..169339 Replicon chromosome
Accession NZ_CP059901
Organism Mumia sp. ZJ1417

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag H4N58_RS00840 Protein ID WP_167000994.1
Coordinates 169037..169339 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag H4N58_RS00835 Protein ID WP_167249463.1
Coordinates 168801..169037 (+) Length 79 a.a.

Genomic Context

H4N58_RS00810H4N58_RS00820H4N58_RS00835H4N58_RS00840H4N58_RS00845H4N58_RS00850H4N58_RS00815H4N58_RS00825H4N58_RS00830H4N58_RS00855H4N58_RS00860
Location: 164353..166458 (2106 bp)
Type: Others
Protein ID: WP_167249469.1
Location: 166911..167573 (663 bp)
Type: Others
Protein ID: WP_167000987.1
Location: 168801..169037 (237 bp)
Type: Antitoxin
Protein ID: WP_167249463.1
Location: 169037..169339 (303 bp)
Type: Toxin
Protein ID: WP_167000994.1
Location: 169683..169916 (234 bp)
Type: Others
Protein ID: WP_167000996.1
Location: 169913..170155 (243 bp)
Type: Others
Protein ID: WP_167249461.1
Location: 166529..166807 (279 bp)
Type: Others
Protein ID: WP_167000986.1
Location: 167579..167917 (339 bp)
Type: Others
Protein ID: WP_167249467.1
Location: 167961..168638 (678 bp)
Type: Others
Protein ID: WP_167249465.1
Location: 170181..170447 (267 bp)
Type: Others
Protein ID: WP_167249460.1
Location: 170605..170904 (300 bp)
Type: Others
Protein ID: WP_167249458.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H4N58_RS00810164353..166458+2106WP_167249469.1iron ABC transporter permease-
H4N58_RS00815166529..166807-279WP_167000986.1GlsB/YeaQ/YmgE family stress response membrane protein-
H4N58_RS00820166911..167573+663WP_167000987.1response regulator transcription factor-
H4N58_RS00825167579..167917-339WP_167249467.1cytoplasmic protein-
H4N58_RS00830167961..168638-678WP_167249465.1Type 1 glutamine amidotransferase-like domain-containing protein-
H4N58_RS00835168801..169037+237WP_167249463.1ribbon-helix-helix domain-containing proteinAntitoxin
H4N58_RS00840169037..169339+303WP_167000994.1type II toxin-antitoxin system PemK/MazF family toxinToxin
H4N58_RS00845169683..169916+234WP_167000996.1ribbon-helix-helix protein, CopG family-
H4N58_RS00850169913..170155+243WP_167249461.1toxin-
H4N58_RS00855170181..170447-267WP_167249460.1hypothetical protein-
H4N58_RS00860170605..170904-300WP_167249458.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-95)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10896.62 Da        Isoelectric Point: 6.4568

>T169325 WP_167000994.1 NZ_CP059901:169037-169339 [Mumia sp. ZJ1417]
MRPIHVARLDKARPVLVLTREVVRPYLNRVTVAPITSTIRGLSTEVPVGPINGLDRDSVVSCDNIVTVPVESVGRQLGFL
LESQEGDLAHAIRAAFDLDL

Download         Length: 303 bp

>T169325 NZ_CP076404:c2048209-2047958 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8475.35 Da        Isoelectric Point: 4.0048

>AT169325 WP_167249463.1 NZ_CP059901:168801-169037 [Mumia sp. ZJ1417]
MSTQIAVRLDDDLVTFVDELVKAGEAPSRAAVVTQALQREQRRTVAERDAAILAAEREDTDMDGLAEFAAGVSMDDHD

Download         Length: 237 bp

>AT169325 NZ_CP076404:c2047961-2047707 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References