169323

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4165932..4166582 Replicon chromosome
Accession NZ_CP059900
Organism Tomitella sp. HY172

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H4F70_RS19265 Protein ID WP_182360543.1
Coordinates 4165932..4166354 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H4F70_RS19270 Protein ID WP_182358398.1
Coordinates 4166367..4166582 (-) Length 72 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4F70_RS19255 4162511..4164655 - 2145 WP_182358396.1 heavy metal translocating P-type ATPase -
H4F70_RS19260 4164971..4165849 + 879 WP_182358397.1 DUF559 domain-containing protein -
H4F70_RS19265 4165932..4166354 - 423 WP_182360543.1 PIN domain-containing protein Toxin
H4F70_RS19270 4166367..4166582 - 216 WP_182358398.1 ribbon-helix-helix domain-containing protein Antitoxin
H4F70_RS19275 4166685..4168772 - 2088 WP_182360544.1 enoyl-CoA hydratase/isomerase family protein -
H4F70_RS19280 4168820..4169818 - 999 WP_182360545.1 NADPH:quinone oxidoreductase family protein -
H4F70_RS19285 4169901..4170926 - 1026 WP_182360546.1 phosphotransferase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-118)

Antitoxin

(4-37)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 14676.41 Da        Isoelectric Point: 4.1508

>T169323 WP_182360543.1 NZ_CP059900:c4166354-4165932 [Tomitella sp. HY172]
MIVDTSALLAFFDASEPDHAAVSAALTAEAGALVVSPFVVAELDYLVAARIGVDAELAVLDELAQGAWDLPEFGAAELAE
ARAVVQRYRDQDIGVADASNVVLAGRYGTDRIATLDHRHFSVLHTDRGGAFTLVPGDAGR

Download         Length: 423 bp

>T169323 NZ_CP076404:2036065-2036439 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7633.68 Da        Isoelectric Point: 11.3450

>AT169323 WP_182358398.1 NZ_CP059900:c4166582-4166367 [Tomitella sp. HY172]
MKKTTLYLPDELKAAVARSAAREGVSEAEVIRRSIARSVGGERPRPRGGLFRSGSPIAREADAHLAGFGER

Download         Length: 216 bp

>AT169323 NZ_CP076404:2035608-2035976 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGATTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References