Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
Location | 4165932..4166582 | Replicon | chromosome |
Accession | NZ_CP059900 | ||
Organism | Tomitella sp. HY172 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | H4F70_RS19265 | Protein ID | WP_182360543.1 |
Coordinates | 4165932..4166354 (-) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | H4F70_RS19270 | Protein ID | WP_182358398.1 |
Coordinates | 4166367..4166582 (-) | Length | 72 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
H4F70_RS19255 | 4162511..4164655 | - | 2145 | WP_182358396.1 | heavy metal translocating P-type ATPase | - |
H4F70_RS19260 | 4164971..4165849 | + | 879 | WP_182358397.1 | DUF559 domain-containing protein | - |
H4F70_RS19265 | 4165932..4166354 | - | 423 | WP_182360543.1 | PIN domain-containing protein | Toxin |
H4F70_RS19270 | 4166367..4166582 | - | 216 | WP_182358398.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
H4F70_RS19275 | 4166685..4168772 | - | 2088 | WP_182360544.1 | enoyl-CoA hydratase/isomerase family protein | - |
H4F70_RS19280 | 4168820..4169818 | - | 999 | WP_182360545.1 | NADPH:quinone oxidoreductase family protein | - |
H4F70_RS19285 | 4169901..4170926 | - | 1026 | WP_182360546.1 | phosphotransferase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 14676.41 Da Isoelectric Point: 4.1508
>T169323 WP_182360543.1 NZ_CP059900:c4166354-4165932 [Tomitella sp. HY172]
MIVDTSALLAFFDASEPDHAAVSAALTAEAGALVVSPFVVAELDYLVAARIGVDAELAVLDELAQGAWDLPEFGAAELAE
ARAVVQRYRDQDIGVADASNVVLAGRYGTDRIATLDHRHFSVLHTDRGGAFTLVPGDAGR
MIVDTSALLAFFDASEPDHAAVSAALTAEAGALVVSPFVVAELDYLVAARIGVDAELAVLDELAQGAWDLPEFGAAELAE
ARAVVQRYRDQDIGVADASNVVLAGRYGTDRIATLDHRHFSVLHTDRGGAFTLVPGDAGR
Download Length: 423 bp
>T169323 NZ_CP076404:2036065-2036439 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
Antitoxin
Download Length: 72 a.a. Molecular weight: 7633.68 Da Isoelectric Point: 11.3450
>AT169323 WP_182358398.1 NZ_CP059900:c4166582-4166367 [Tomitella sp. HY172]
MKKTTLYLPDELKAAVARSAAREGVSEAEVIRRSIARSVGGERPRPRGGLFRSGSPIAREADAHLAGFGER
MKKTTLYLPDELKAAVARSAAREGVSEAEVIRRSIARSVGGERPRPRGGLFRSGSPIAREADAHLAGFGER
Download Length: 216 bp
>AT169323 NZ_CP076404:2035608-2035976 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGATTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGATTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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