Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 1767661..1768151 Replicon chromosome
Accession NZ_CP059900
Organism Tomitella sp. HY172

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H4F70_RS08325 Protein ID WP_182359803.1
Coordinates 1767879..1768151 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag H4F70_RS08320 Protein ID WP_182360264.1
Coordinates 1767661..1767882 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4F70_RS08305 1763921..1766416 + 2496 WP_182359800.1 SEC-C domain-containing protein -
H4F70_RS08310 1766542..1767396 + 855 WP_182359801.1 hypothetical protein -
H4F70_RS08315 1767422..1767622 - 201 WP_182359802.1 hypothetical protein -
H4F70_RS08320 1767661..1767882 + 222 WP_182360264.1 ribbon-helix-helix domain-containing protein Antitoxin
H4F70_RS08325 1767879..1768151 + 273 WP_182359803.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H4F70_RS08330 1768158..1768514 - 357 WP_182359804.1 DUF3883 domain-containing protein -
H4F70_RS08335 1768697..1769098 + 402 WP_182359805.1 helix-turn-helix transcriptional regulator -
H4F70_RS08340 1769141..1769287 + 147 WP_182359806.1 hypothetical protein -
H4F70_RS08345 1769263..1769466 - 204 WP_182348219.1 hypothetical protein -
H4F70_RS08350 1769690..1770160 + 471 WP_182359807.1 cupin domain-containing protein -
H4F70_RS08355 1770251..1770745 - 495 WP_182348221.1 transcription elongation factor GreA -
H4F70_RS08360 1771096..1771581 - 486 WP_182359808.1 DUF4307 domain-containing protein -
H4F70_RS08365 1771852..1772730 + 879 WP_182360265.1 mycothiol conjugate amidase Mca -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-40)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10558.08 Da        Isoelectric Point: 10.2969

>T169317 WP_182359803.1 NZ_CP059900:1767879-1768151 [Tomitella sp. HY172]
VTGWQLRTTTRFDRAARKLDRQVLRRVRTYLDEVCQLDDPRLRGKPLTAGLSGYWRYRIGDWRVIAEIRESELIVLAIGL
GHRSEIYGND

Download         Length: 273 bp

>T169317 NZ_CP076404:c1251391-1251284 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8615.57 Da        Isoelectric Point: 4.5702

>AT169317 WP_182360264.1 NZ_CP059900:1767661-1767882 [Tomitella sp. HY172]
MSMSIRLTSEEEARLDRLAKRTGRSKSFYVREALREHLDELEEKYWGDAVVQEWEASDKTSRPAQELWDELGV

Download         Length: 222 bp

>AT169317 NZ_CP076404:1251439-1251505 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References