Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 822482..823143 Replicon plasmid unnamed
Accession NZ_CP059897
Organism Ciceribacter thiooxidans strain F43B

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H4I97_RS21770 Protein ID WP_182307810.1
Coordinates 822482..822886 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H4I97_RS21775 Protein ID WP_182307811.1
Coordinates 822883..823143 (-) Length 87 a.a.

Genomic Context

H4I97_RS21745H4I97_RS21750H4I97_RS21765H4I97_RS21780H4I97_RS21785H4I97_RS21755H4I97_RS21760H4I97_RS21770H4I97_RS21775H4I97_RS21790H4I97_RS21795H4I97_RS21800
Location: 818162..819226 (1065 bp)
Type: Others
Protein ID: WP_182307807.1
Location: 819591..820532 (942 bp)
Type: Others
Protein ID: WP_182307808.1
Location: 821745..822373 (629 bp)
Type: Others
Protein ID: Protein_737
Location: 823470..823730 (261 bp)
Type: Others
Protein ID: Protein_740
Location: 824399..824722 (324 bp)
Type: Others
Protein ID: WP_182307812.1
Location: 820612..821118 (507 bp)
Type: Others
Protein ID: WP_182307809.1
Location: 821115..821600 (486 bp)
Type: Others
Protein ID: WP_112691241.1
Location: 822482..822886 (405 bp)
Type: Toxin
Protein ID: WP_182307810.1
Location: 822883..823143 (261 bp)
Type: Antitoxin
Protein ID: WP_182307811.1
Location: 824924..826831 (1908 bp)
Type: Others
Protein ID: WP_182307813.1
Location: 826828..827058 (231 bp)
Type: Others
Protein ID: WP_182307814.1
Location: 827048..827329 (282 bp)
Type: Others
Protein ID: WP_112691248.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H4I97_RS21745818162..819226+1065WP_182307807.1toprim domain-containing protein-
H4I97_RS21750819591..820532+942WP_182307808.1DUF2493 domain-containing protein-
H4I97_RS21755820612..821118-507WP_182307809.1RES family NAD+ phosphorylase-
H4I97_RS21760821115..821600-486WP_112691241.1DUF2384 domain-containing protein-
H4I97_RS21765821745..822373+629Protein_737plasmid pRiA4b ORF-3 family protein-
H4I97_RS21770822482..822886-405WP_182307810.1type II toxin-antitoxin system VapC family toxinToxin
H4I97_RS21775822883..823143-261WP_182307811.1antitoxinAntitoxin
H4I97_RS21780823470..823730+261Protein_740type II toxin-antitoxin system Phd/YefM family antitoxin-
H4I97_RS21785824399..824722+324WP_182307812.1DUF736 family protein-
H4I97_RS21790824924..826831-1908WP_182307813.1Ti-type conjugative transfer system protein TraG-
H4I97_RS21795826828..827058-231WP_182307814.1conjugal transfer protein TraD-
H4I97_RS21800827048..827329-282WP_112691248.1TraC family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-adeG1..13820591382059


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(8-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14553.70 Da        Isoelectric Point: 6.8794

>T169311 WP_182307810.1 NZ_CP059897:c822886-822482 [Ciceribacter thiooxidans]
VISHLLDTNTVIALIGRKSNALVSRVLHSPQGSIGLPTVVAYELYFGAQKSAKVQHNLETLRLFMADFPILEFDRNDAFV
AGEIRAALAAKGTPIGPYDVLIAGQAKARGLTLVTNNVGEFNRVDNLHVEDWSL

Download         Length: 405 bp

>T169311 NZ_CP076386:4044727-4044984 [Dickeya dadantii]
ATGCCTGAAATTGACAGACTGGCAGGGCTCATTTTCTATCTGTATTTTTACGATGATGACAGGCACCACCTGCCTCATGT
ACATGTCTGTTACGGTGATGATGAGTTGATCATCGCGATAGATACTGGCGTTGAGATTGAAGGTTATTTGCCCAATAGCA
AGCGTAAGATGGCGATTAAGCATATCAACACGCATCGGCAACATTTGCTGGAAATGTGGAAACTGGCAGTGAAAGGCCGT
CATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9826.98 Da        Isoelectric Point: 4.6631

>AT169311 WP_182307811.1 NZ_CP059897:c823143-822883 [Ciceribacter thiooxidans]
MPHFARVFQSGNSQAVRLPKEFRFNVERVEITQEGDALILRPHVEAGEPWSSLKAALARGMSEDFMESGREQPEQQDRPE
LDAVFQ

Download         Length: 261 bp

>AT169311 NZ_CP076386:4044993-4045481 [Dickeya dadantii]
ATGCATAAAATCATCGATGTTGATGTGACTGGTGACTTTACCTTGCGGCTGACCTATGAGGACGGCTTGATCTGTGATGT
CGATCTTTACCAATACGCCCCTGATCCGGTGTTTTCGAACGCCAGCCTATTTATCAAGTTTGGCCTGCTGCCGGATGGCG
CGCTGGAATGGCAGCCGGATATTAAGATTTCCGCGTCAGACTTGCGGAAAAAAGGCGTGTATGTCGGCCACACGCTGGCG
GTGCGAGAAAGGCGCTTCGCTGATGTCATCTCCCGCGCCTTCTATGACGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
GGCGGCGTTGAAAACCGCGGTGGAAAAACATGGCAACAGCACCGTAGCCAAAGAGGCGGGGGCGAAAAGCCGCACCAGCC
TGTATAAGTCACTGAATAAGAATACCAACGTCAGCCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAACTGGAA
GAGAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References