Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2403163..2403751 Replicon chromosome
Accession NZ_CP059896
Organism Ciceribacter thiooxidans strain F43B

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag H4I97_RS11700 Protein ID WP_182307622.1
Coordinates 2403464..2403751 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag H4I97_RS11695 Protein ID WP_148175048.1
Coordinates 2403163..2403462 (-) Length 100 a.a.

Genomic Context

H4I97_RS11665H4I97_RS11675H4I97_RS11710H4I97_RS11670H4I97_RS11680H4I97_RS11685H4I97_RS11690H4I97_RS11695H4I97_RS11700H4I97_RS11705
Location: 2399007..2399738 (732 bp)
Type: Others
Protein ID: WP_182304823.1
Location: 2400853..2401590 (738 bp)
Type: Others
Protein ID: WP_182304825.1
Location: 2406285..2407042 (758 bp)
Type: Others
Protein ID: Protein_2294
Location: 2400352..2400765 (414 bp)
Type: Others
Protein ID: WP_182304824.1
Location: 2401615..2401932 (318 bp)
Type: Others
Protein ID: WP_182304826.1
Location: 2402032..2402562 (531 bp)
Type: Others
Protein ID: WP_182304827.1
Location: 2402631..2403152 (522 bp)
Type: Others
Protein ID: WP_182304828.1
Location: 2403163..2403462 (300 bp)
Type: Antitoxin
Protein ID: WP_148175048.1
Location: 2403464..2403751 (288 bp)
Type: Toxin
Protein ID: WP_182307622.1
Location: 2403823..2405931 (2109 bp)
Type: Others
Protein ID: WP_182304829.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H4I97_RS116652399007..2399738+732WP_182304823.1hypothetical protein-
H4I97_RS116702400352..2400765-414WP_182304824.1helix-turn-helix domain-containing protein-
H4I97_RS116752400853..2401590+738WP_182304825.1cation transporter-
H4I97_RS116802401615..2401932-318WP_182304826.1hypothetical protein-
H4I97_RS116852402032..2402562-531WP_182304827.1hypothetical protein-
H4I97_RS116902402631..2403152-522WP_182304828.1DUF1697 domain-containing protein-
H4I97_RS116952403163..2403462-300WP_148175048.1putative addiction module antidote proteinAntitoxin
H4I97_RS117002403464..2403751-288WP_182307622.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H4I97_RS117052403823..2405931-2109WP_182304829.1S9 family peptidase-
H4I97_RS117102406285..2407042+758Protein_2294polysaccharide deacetylase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10893.75 Da        Isoelectric Point: 10.3097

>T169310 WP_182307622.1 NZ_CP059896:c2403751-2403464 [Ciceribacter thiooxidans]
MIEIRQHPDFAGWLRKLKDRQAQTRIAIRLVRLQSGLMGDVKYFGGIGEVRIDYGPGYRLYFVRRGEALIILLCGGDKAS
QEKDIRRAMDLAKDV

Download         Length: 288 bp

>T169310 NZ_CP076386:3982362-3982676 [Dickeya dadantii]
ATGCAATTCACCGTATACGGTAATACTGGGAAAAGCGCCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAGTTGAATCGTCGGATAGTGATCCCGTTGCTCCCTGTTGAAAAGTACCCCGCAGGCCGCCGACCGGATCGCCTTGTCC
CTGTCGTCAGGCTGACGGACGGCAAAGAGTACGCCGTAATGACGCACGAGCTGGCAAGTATCCCTGTCCAGGCTCTGGGG
GCGGTATTTTGTGATGCGTCTCAGTATCGTACTCAGATAAAGGCCGCAATAGACTTCCTCATCGACGGGATCTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10254.66 Da        Isoelectric Point: 4.5702

>AT169310 WP_148175048.1 NZ_CP059896:c2403462-2403163 [Ciceribacter thiooxidans]
MATETIPFDASEFFADAEAQAALLTDAFESGDAAYIANALGIIAKAKGMTRVAREAGVTREALYKALSERGDPKFSTILG
VAKALGLKFTVTPASGPAE

Download         Length: 300 bp

>AT169310 NZ_CP076386:3982123-3982359 [Dickeya dadantii]
ATGACCGCGAAACAACGTAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGGTCCGGGCGCGTGAAGCTGG
TATTAACCTGAGTGCCACCCTGACAGCTGCCCTGGATACAGAGCTTCGCTACCATGAAGCGAAAAAATGGCAGGAAGAGA
ACAGGGAGGCCATCGACGCATTAAATCGCTTTCATGATGAGCACGGCTGTTTCAGCGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References