Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029001..2029146 Replicon chromosome
Accession NZ_CP059889
Organism Klebsiella pneumoniae subsp. pneumoniae strain KP18069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029037..2029139 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029001..2029146 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4N62_RS09775 2024131..2026191 + 2061 WP_004151449.1 oligopeptidase B -
H4N62_RS09780 2026195..2026854 - 660 WP_020324964.1 exodeoxyribonuclease X -
H4N62_RS09785 2026933..2027163 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H4N62_RS09790 2027276..2027650 + 375 WP_004151448.1 CopC domain-containing protein YobA -
H4N62_RS09795 2027654..2028523 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
H4N62_RS09800 2028540..2028878 + 339 WP_002911404.1 YebY family protein -
- 2029001..2029146 - 146 - - Antitoxin
- 2029037..2029139 + 103 - - Toxin
H4N62_RS09805 2029515..2029658 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H4N62_RS09810 2029763..2030731 - 969 WP_004151446.1 VirK/YbjX family protein -
H4N62_RS09815 2030888..2031541 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
H4N62_RS09820 2031538..2031729 - 192 WP_002911395.1 YebW family protein -
H4N62_RS09825 2031827..2032066 - 240 WP_002911393.1 YebV family protein -
H4N62_RS09830 2032182..2033615 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T169290 NZ_CP059889:2029037-2029139 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT169290 NZ_CP059889:c2029146-2029001 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References