Detailed information of TA system TA169286

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 3574623..3575164
• Replicon: chromosome
• Accession: NZ_CP059888
• Organism: Flocculibacter collagenilyticus strain SM1988

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HUU81_RS15855
• Protein ID: WP_199609871.1
• Coordinates: 3574623..3574919 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HUU81_RS15860
• Protein ID: WP_199609872.1
• Coordinates: 3574907..3575164 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HUU81_RS15840	3569770..3573003	-	3234	WP_199609868.1	ligand-binding sensor domain-containing diguanylate cyclase	-
HUU81_RS15845	3573156..3573641	-	486	WP_199609869.1	transcription elongation factor GreB	-
HUU81_RS15850	3573807..3574382	-	576	WP_199609870.1	hypothetical protein	-
HUU81_RS15855	3574623..3574919	-	297	WP_199609871.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HUU81_RS15860	3574907..3575164	-	258	WP_199609872.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HUU81_RS15865	3575448..3576236	-	789	WP_199609873.1	trypsin-like serine protease	-
HUU81_RS15870	3576390..3577007	-	618	WP_199609874.1	LysE family translocator	-
HUU81_RS15875	3577119..3577490	-	372	WP_199609875.1	DUF4288 domain-containing protein	-
HUU81_RS15880	3577502..3577804	-	303	WP_199609876.1	DUF1330 domain-containing protein	-
HUU81_RS15885	3577837..3578226	-	390	WP_199609877.1	DoxX-like family protein	-
HUU81_RS15890	3578264..3579784	-	1521	WP_199609878.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-66)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11448.32 Da
• Isoelectric Point: 5.7121

>T169286 WP_199609871.1 NZ_CP059888:c3574919-3574623 [Flocculibacter collagenilyticus]
MAEIIWTRPALDELNEIADYIAVANLAAAQKLVQTIFDKTERLETHPESGRVPPEIPTLNYREIVVSPCRIFYKLDGNRL
FILHVMRQEQDLRRFLLI

Nucleotide

• Length: 297 bp

>T169286 NZ_CP076378:c2895606-2895028 [Mycobacterium intracellulare]
ATGCAGCGACTTGACCTGGTAGTCGGGCCGAACGGTGCCGGCAAGTCGACCTTCATCGCGTTCACGCTGGCGCCGCTGTT
GCCCGGCAGCCCGGTCGTCAACGCCGATGAGATCGCAAGGCAGCGCTGGCCGGGGGAGGCGGCGGGGCGCGCCTACGACG
CCGCGCAAATCGCCGCCGCCACGCGCGCGAAGTTGATCGACCTGGGGCGGTCGTTCATCGCGGAGACCGTGTTTTCCCAC
CCGTCGAAGCTGGACCTCGTCCGCACCGCCCACCGAGCGGGCTTCACCGCCGTCCTGCACGCGATGCTCATCCCGGAAGA
CCTTGCCGTCGAACGTGTCCGGCACCGCGTGCGGGCCGGCGGCCACGACGTACCGGAAACCAAGGTCCGCGAGCGCCATC
GTCGCTTGTGGACACCGGTCACCGACGCCATCGCGCTCTCCGACGTCGCCACCGTCTACGACAGCGGCCGGCTGCGCGGG
CCGCGCATTGTCGCCCGCCTCAGCGGCGGCATGACGATCGGTTCACCGGACTGGCCGGCGTGGGCTCCGGAGATCTTGCG
GTCGCGCTGGCCGGACTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9809.37 Da
• Isoelectric Point: 7.2030

>AT169286 WP_199609872.1 NZ_CP059888:c3575164-3574907 [Flocculibacter collagenilyticus]
MKVELVTTLKRQATKILADLHSTKEPVLITEHGKPSAYLVDVEDYEMMQRRMAILEGIARGEQAIRNDQVVTNEQAKEQM
NKWLK

Nucleotide

• Length: 258 bp

>AT169286 NZ_CP076378:c2896020-2895631 [Mycobacterium intracellulare]
ATGGCCGACGCTCCCGATCGTGTGACCCGCGTGGCGTCCGACCTGATGGACAGCGCGGCCTCCGAAGGCGCCCGCCAGAG
CCGTTCGGCCAAGCAGCAACTCGACCACTGGGCGCGTGTCGGGCGCGCGGTGTCCAGCCAGCACACCGCCTCGCGGCGGC
GGGTCGAGGCCGCGCTGGCCGGCCAGCTGGCGACCGGCGAACTCACCGTCGAGGAAGGCGTGGTGTTCAACGCCGAGATC
TCCGCCGCCATCGAAGAAAGCCTGGTGCACGCCGACTACGGGGCGACGCTGGCCGGGCATGGCGTCACCACGGTCGCCCT
CAACGAGGACGGCGACATCGTCGAGCACCGGCCCGATGGCGCCGCCGTGGTGCTGGCGCGCGGGCGCTGA