Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 2118734..2119265 Replicon chromosome
Accession NZ_CP059851
Organism Sandaracinobacter sp. M6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H3309_RS10685 Protein ID WP_182294705.1
Coordinates 2118984..2119265 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag H3309_RS10680 Protein ID WP_182294704.1
Coordinates 2118734..2118997 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3309_RS10645 2114519..2114746 - 228 WP_182294698.1 hypothetical protein -
H3309_RS10650 2114910..2115557 - 648 WP_182294699.1 NADH-quinone oxidoreductase subunit NuoE -
H3309_RS10655 2115499..2115822 - 324 WP_182294700.1 hypothetical protein -
H3309_RS10660 2115819..2117045 - 1227 WP_182294701.1 NADH-quinone oxidoreductase subunit D -
H3309_RS10665 2117042..2117659 - 618 WP_182294702.1 NADH-quinone oxidoreductase subunit C -
H3309_RS10670 2117656..2118198 - 543 WP_207791493.1 NADH-quinone oxidoreductase subunit NuoB -
H3309_RS10675 2118195..2118590 - 396 WP_182298671.1 NADH-quinone oxidoreductase subunit A -
H3309_RS10680 2118734..2118997 + 264 WP_182294704.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H3309_RS10685 2118984..2119265 + 282 WP_182294705.1 type II toxin-antitoxin system YafQ family toxin Toxin
H3309_RS10690 2119269..2121236 - 1968 WP_182294706.1 S9 family peptidase -
H3309_RS10695 2121314..2123053 + 1740 WP_182294707.1 gamma-glutamyltransferase -
H3309_RS10700 2123153..2123566 - 414 WP_182294708.1 DUF2442 domain-containing protein -
H3309_RS10705 2123559..2123798 - 240 WP_182294709.1 DUF4160 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-78)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10946.53 Da        Isoelectric Point: 10.3440

>T169274 WP_182294705.1 NZ_CP059851:2118984-2119265 [Sandaracinobacter sp. M6]
MRTIERTTTFKRDWKRELRGRHAATPARDVTGLLTLLVHDQPLEPRHRDHALTGNWKDHRDCHVKPDLVLIYRKPDPETL
QLVRLGSHAELGW

Download         Length: 282 bp

>T169274 NZ_CP076344:c3748984-3748577 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTACAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9284.68 Da        Isoelectric Point: 4.6325

>AT169274 WP_182294704.1 NZ_CP059851:2118734-2118997 [Sandaracinobacter sp. M6]
MSSNALVQTRINETVKQQAATVLATMGLTVSDAVRMMLTRVAHDKALPFDPLVPNAETIAAMEQARAGGLPRFKSVDALM
ADLDADD

Download         Length: 264 bp

>AT169274 NZ_CP076344:c3749231-3748965 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATTCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References