Detailed information of TA system TA169272

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 1174479..1175152
• Replicon: chromosome
• Accession: NZ_CP059851
• Organism: Sandaracinobacter sp. M6

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: H3309_RS05910
• Protein ID: WP_207791563.1
• Coordinates: 1174679..1175152 (+)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: H3309_RS16945
• Protein ID: WP_207791599.1
• Coordinates: 1174479..1174643 (+)
• Length: 55 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H3309_RS05895	1172807..1173619	+	813	WP_207791562.1	sterol desaturase family protein	-
H3309_RS05900	1173616..1174257	+	642	WP_182297821.1	lysoplasmalogenase	-
H3309_RS16945	1174479..1174643	+	165	WP_207791599.1	DUF2384 domain-containing protein	Antitoxin
H3309_RS05910	1174679..1175152	+	474	WP_207791563.1	RES domain-containing protein	Toxin
H3309_RS05915	1175269..1176021	+	753	WP_182297823.1	30S ribosomal protein S2	-
H3309_RS05920	1176236..1177162	+	927	WP_182297824.1	elongation factor Ts	-
H3309_RS05925	1177257..1177973	+	717	WP_182297825.1	UMP kinase	-
H3309_RS05930	1177991..1178560	+	570	WP_182297826.1	ribosome recycling factor	-
H3309_RS05935	1178638..1179306	+	669	WP_182298527.1	di-trans,poly-cis-decaprenylcistransferase	-
H3309_RS05940	1179306..1180106	+	801	WP_182297827.1	phosphatidate cytidylyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-151)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (2-51)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 16473.52 Da
• Isoelectric Point: 7.3186

>T169272 WP_207791563.1 NZ_CP059851:1174679-1175152 [Sandaracinobacter sp. M6]
VPAWSWAPLSGEGAARFGGRWNARGQAAIYGALELATAWSEYNQGLSQHPGLVARLHVRGARLADVRDADLRVAHGVPDD
LGGDSWRAAMTAAGVAPTQAAALRMMAAGYDGLLAPSFMAPGGKTAVLWRWNRDGAPGVMVEDPEGRLPRDGASWSG

Nucleotide

• Length: 474 bp

>T169272 NZ_CP076344:c2825877-2825626 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 55 a.a.
• Molecular weight: 5850.65 Da
• Isoelectric Point: 6.4510

>AT169272 WP_207791599.1 NZ_CP059851:1174479-1174643 [Sandaracinobacter sp. M6]
MAADMSGSPERAALWFKHQPLPGWAGKTARDLIAEGRAQDVMDYLEAVRAGVHA

Nucleotide

• Length: 165 bp

>AT169272 NZ_CP076344:c2825629-2825375 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA