Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2140270..2140538 Replicon chromosome
Accession NZ_CP059840
Organism Escherichia coli strain E2348/69

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2140398..2140500 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2140270..2140538 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4J01_RS10600 2136823..2137485 - 663 WP_000944249.1 exodeoxyribonuclease X -
H4J01_RS10605 2137509..2138165 - 657 WP_000011646.1 carbon-nitrogen hydrolase family protein -
H4J01_RS10610 2138267..2138497 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4J01_RS10615 2138636..2139010 + 375 WP_000204700.1 CopC domain-containing protein YobA -
H4J01_RS10620 2139014..2139886 + 873 WP_000879263.1 copper homeostasis membrane protein CopD -
H4J01_RS10625 2139899..2140240 + 342 WP_000976470.1 YebY family protein -
- 2140270..2140538 - 269 - - Antitoxin
- 2140398..2140500 + 103 - - Toxin
H4J01_RS10630 2140635..2141291 + 657 WP_000812706.1 protein-serine/threonine phosphatase -
H4J01_RS10635 2141292..2141483 - 192 WP_001296140.1 YebW family protein -
H4J01_RS10640 2141588..2141824 - 237 WP_001295499.1 DUF1480 family protein -
H4J01_RS10645 2141942..2143381 - 1440 WP_001339709.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T169230 NZ_CP059840:2140398-2140500 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT169230 NZ_CP059840:c2140538-2140270 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References