Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 603221..603492 Replicon chromosome
Accession NZ_CP059835
Organism Escherichia coli strain tcmA_3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 603259..603362 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 603221..603492 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GQF93_RS02910 600378..601817 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GQF93_RS02915 601935..602171 + 237 WP_001295499.1 YebV family protein -
GQF93_RS02920 602276..602467 + 192 WP_001296140.1 YebW family protein -
GQF93_RS02925 602468..603124 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 603221..603492 + 272 - - Antitoxin
- 603259..603362 - 104 - - Toxin
GQF93_RS02930 603520..603861 - 342 WP_000976492.1 YebY family protein -
GQF93_RS02935 603874..604746 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GQF93_RS02940 604750..605124 - 375 WP_000204699.1 CopC domain-containing protein YobA -
GQF93_RS02945 605263..605493 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GQF93_RS02950 605595..606251 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
GQF93_RS02955 606275..606937 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169184 NZ_CP059835:c603362-603259 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169184 NZ_CP059835:603221-603492 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References