169123

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2718006..2718471 Replicon chromosome
Accession NZ_CP059738
Organism Pseudomonas sp. 29A

Toxin (Protein)


Gene name relE Uniprot ID A0A7H8GNS0
Locus tag H3303_RS12105 Protein ID WP_016983362.1
Coordinates 2718006..2718290 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7H8GW22
Locus tag H3303_RS12110 Protein ID WP_026000469.1
Coordinates 2718280..2718471 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3303_RS12075 2713256..2713630 + 375 WP_007919395.1 type II secretion system GspH family protein -
H3303_RS12080 2713605..2714144 + 540 WP_175554748.1 type II secretion system protein -
H3303_RS12085 2714141..2714533 + 393 WP_175554747.1 curli production assembly/transport protein CsgE -
H3303_RS12090 2714530..2714961 + 432 WP_016987875.1 curli production assembly protein CsgF -
H3303_RS12095 2714991..2715851 + 861 WP_026000822.1 curli production assembly/transporter CsgG -
H3303_RS12100 2716703..2717176 + 474 WP_175554746.1 hypothetical protein -
H3303_RS12105 2718006..2718290 - 285 WP_016983362.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H3303_RS12110 2718280..2718471 - 192 WP_026000469.1 hypothetical protein Antitoxin
H3303_RS12115 2718798..2720249 - 1452 WP_175554745.1 curlin -
H3303_RS12120 2720277..2720741 - 465 WP_175554744.1 curlin -
H3303_RS12125 2720814..2723048 - 2235 WP_175554743.1 cadherin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.69 Da        Isoelectric Point: 10.6629

>T169123 WP_016983362.1 NZ_CP059738:c2718290-2718006 [Pseudomonas sp. 29A]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALCWHPHLYRKGRSPGTREIVVSPNYLVVYQVADQIEIVS
ILHARQEYPRRDPG

Download         Length: 285 bp

>T169123 NZ_CP076279:c3918591-3918316 [Escherichia coli]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7146.94 Da        Isoelectric Point: 3.8576

>AT169123 WP_026000469.1 NZ_CP059738:c2718471-2718280 [Pseudomonas sp. 29A]
MIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD

Download         Length: 192 bp

>AT169123 NZ_CP076279:c3918319-3917960 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H8GNS0

Antitoxin

Source ID Structure
AlphaFold DB A0A7H8GW22

References