Detailed information of TA system TA169113

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1858655..1859193
• Replicon: chromosome
• Accession: NZ_CP059733
• Organism: Thalassomonas viridans strain XOM25

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SG34_RS08310
• Protein ID: WP_084723942.1
• Coordinates: 1858918..1859193 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SG34_RS08305
• Protein ID: WP_201778252.1
• Coordinates: 1858655..1858918 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SG34_RS08295 (SG34_008265)	1854737..1857085	-	2349	WP_044839321.1	winged helix-turn-helix domain-containing protein	-
SG34_RS08300 (SG34_008270)	1857790..1858518	+	729	WP_044839375.1	DNA/RNA non-specific endonuclease	-
SG34_RS08305 (SG34_008275)	1858655..1858918	+	264	WP_201778252.1	ribbon-helix-helix domain-containing protein	Antitoxin
SG34_RS08310 (SG34_008280)	1858918..1859193	+	276	WP_084723942.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SG34_RS08315 (SG34_008285)	1859386..1860552	+	1167	WP_044839323.1	FAD-dependent oxidoreductase	-
SG34_RS08320 (SG34_008290)	1860695..1860913	-	219	WP_044839324.1	hypothetical protein	-
SG34_RS08370 (SG34_008340)	1862471..1862821	-	351	WP_044839325.1	DUF3718 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-44)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 11028.84 Da
• Isoelectric Point: 10.9479

>T169113 WP_084723942.1 NZ_CP059733:1858918-1859193 [Thalassomonas viridans]
MEIKWTIKSLSDLNRLFEFLAPVNKQAAAKTIQSLTQAPTRIIHQPRIGERLDEFEPKEVRRLLVGHYEMRYELRNNTLF
ILRIWHTRERR

Nucleotide

• Length: 276 bp

>T169113 NZ_CP076279:c1559602-1559408 [Escherichia coli]
ATGCGGTATGAAAAAGTCAAACCATGCCCTTTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
CGCGAAGTGTAACGGATGCGAATCCCGAACCGGCTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9860.13 Da
• Isoelectric Point: 4.6486

>AT169113 WP_201778252.1 NZ_CP059733:1858655-1858918 [Thalassomonas viridans]
MMETKVITAHVPISLAEKVDNLANRLERSKAWVMKQALAAWVEQEEERHRLTLEAIADVDENNVIDHQSVQAWAESLSSD
TPLPTPR

Nucleotide

• Length: 264 bp

>AT169113 NZ_CP076279:1559231-1559409 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCCGATTTGGTTAACTTTGTTTTTGAGTACCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT