Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1618326..1618870 Replicon chromosome
Accession NZ_CP059733
Organism Thalassomonas viridans strain XOM25

Toxin (Protein)


Gene name relE Uniprot ID A0A0D8DIM2
Locus tag SG34_RS07090 Protein ID WP_044837251.1
Coordinates 1618326..1618598 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D8DGA2
Locus tag SG34_RS07095 Protein ID WP_044837250.1
Coordinates 1618598..1618870 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SG34_RS07065 (SG34_007020) 1613451..1613957 - 507 WP_044837256.1 hypothetical protein -
SG34_RS07070 (SG34_007025) 1614403..1615479 + 1077 WP_044837255.1 kelch repeat-containing protein -
SG34_RS07075 (SG34_007030) 1615581..1616744 - 1164 WP_044837254.1 hypothetical protein -
SG34_RS07080 (SG34_007035) 1617091..1617837 + 747 WP_044837253.1 LamG domain-containing protein -
SG34_RS07085 (SG34_007040) 1617961..1618329 + 369 WP_044837252.1 hypothetical protein -
SG34_RS07090 (SG34_007045) 1618326..1618598 - 273 WP_044837251.1 type II toxin-antitoxin system YafQ family toxin Toxin
SG34_RS07095 (SG34_007050) 1618598..1618870 - 273 WP_044837250.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
SG34_RS07100 (SG34_007055) 1619255..1619764 + 510 WP_044837249.1 DUF4231 domain-containing protein -
SG34_RS07105 (SG34_007060) 1620235..1621668 + 1434 WP_044837248.1 TIR domain-containing protein -
SG34_RS07110 (SG34_007065) 1621794..1622024 + 231 WP_152647072.1 hypothetical protein -
SG34_RS07115 (SG34_007070) 1622177..1622818 + 642 WP_044837246.1 hypothetical protein -
SG34_RS07120 (SG34_007075) 1622898..1623113 + 216 WP_044837245.1 AbrB family transcriptional regulator -
SG34_RS07125 (SG34_007080) 1623113..1623547 + 435 WP_044837244.1 type II toxin-antitoxin system VapC family toxin -
SG34_RS07130 (SG34_007085) 1623595..1623816 + 222 WP_044837243.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-83)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10330.17 Da        Isoelectric Point: 10.0393

>T169112 WP_044837251.1 NZ_CP059733:c1618598-1618326 [Thalassomonas viridans]
MLALEYASQFKKDFKKVAKLPIPDVIEVGHVIKQLQLGQTLPKKYVDHSLSGNWQGFRDCHIKPDLVLIYKIDNVSLKLA
RIGTHSELFR

Download         Length: 273 bp

>T169112 NZ_CP076279:c1358570-1358463 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9740.15 Da        Isoelectric Point: 4.7672

>AT169112 WP_044837250.1 NZ_CP059733:c1618870-1618598 [Thalassomonas viridans]
MKTEMLSTRIDPDTKLAFTRVCEDMGLSTSQALKLFAKAVINHGGIPFELKAKTPNALTAAAINELETGNGKTANTVEEL
FNDLDIDSLK

Download         Length: 273 bp

>AT169112 NZ_CP076279:1358617-1358683 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D8DIM2

Antitoxin

Source ID Structure
AlphaFold DB A0A0D8DGA2

References