Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | omega-epsilon-zeta/- |
| Location | 619564..621143 | Replicon | chromosome |
| Accession | NZ_CP059710 | ||
| Organism | Xanthomonas oryzae pv. oryzicola strain ML5 | ||
Toxin (Protein)
| Gene name | avrRxo1 | Uniprot ID | A0A5E8KQ48 |
| Locus tag | H4J00_RS02865 | Protein ID | WP_047340211.1 |
| Coordinates | 619564..620829 (+) | Length | 422 a.a. |
Antitoxin (Protein)
| Gene name | arc1 | Uniprot ID | A0A0C5UZA4 |
| Locus tag | H4J00_RS02870 | Protein ID | WP_044749828.1 |
| Coordinates | 620847..621143 (+) | Length | 99 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H4J00_RS02845 (H4J00_02845) | 616836..617054 | + | 219 | WP_076342548.1 | Imm31 family immunity protein | - |
| H4J00_RS02850 (H4J00_02850) | 617100..617216 | - | 117 | Protein_542 | IS30 family transposase | - |
| H4J00_RS02855 (H4J00_02855) | 617634..618659 | + | 1026 | Protein_543 | hemagglutinin repeat-containing protein | - |
| H4J00_RS02860 (H4J00_02860) | 618659..619189 | + | 531 | Protein_544 | IS30 family transposase | - |
| H4J00_RS02865 (H4J00_02865) | 619564..620829 | + | 1266 | WP_047340211.1 | zeta toxin family type III secretion system effector XopAJ/AvrRxo1 | Toxin |
| H4J00_RS02870 (H4J00_02870) | 620847..621143 | + | 297 | WP_044749828.1 | hypothetical protein | Antitoxin |
| H4J00_RS02875 (H4J00_02875) | 621365..621631 | + | 267 | Protein_547 | transposase | - |
| H4J00_RS02880 (H4J00_02880) | 621698..622123 | - | 426 | Protein_548 | integrase core domain-containing protein | - |
| H4J00_RS02885 (H4J00_02885) | 622192..623294 | + | 1103 | WP_154235785.1 | IS3 family transposase | - |
| H4J00_RS02890 (H4J00_02890) | 623324..623401 | + | 78 | Protein_550 | anti-sigma factor antagonist | - |
| H4J00_RS02895 (H4J00_02895) | 623496..623671 | + | 176 | Protein_551 | HAD family hydrolase | - |
| H4J00_RS02900 (H4J00_02900) | 623887..624639 | - | 753 | WP_024712407.1 | YceI family protein | - |
| H4J00_RS02905 (H4J00_02905) | 624850..625440 | - | 591 | WP_014504809.1 | malonic semialdehyde reductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 616836..631074 | 14238 | |
| - | inside | IScluster/Tn | - | - | 618776..623294 | 4518 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 422 a.a. Molecular weight: 45159.73 Da Isoelectric Point: 6.9140
>T169062 WP_047340211.1 NZ_CP059710:619564-620829 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAATHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAATHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI
Download Length: 1266 bp
>T169062 NZ_CP076274:c2316829-2316578 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 99 a.a. Molecular weight: 11327.83 Da Isoelectric Point: 5.2138
>AT169062 WP_044749828.1 NZ_CP059710:620847-621143 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS
Download Length: 297 bp
>AT169062 NZ_CP076274:c2316581-2316327 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A5E8KQ48 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5UZA4 |