169061

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 389258..389619 Replicon chromosome
Accession NZ_CP059710
Organism Xanthomonas oryzae pv. oryzicola strain ML5

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag H4J00_RS01755 Protein ID WP_011257368.1
Coordinates 389485..389619 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag H4J00_RS01750 Protein ID WP_011407410.1
Coordinates 389258..389410 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4J00_RS01725 (H4J00_01715) 385600..386283 - 684 WP_014505034.1 dTMP kinase -
H4J00_RS01730 386763..387300 - 538 Protein_330 GTPase -
H4J00_RS01735 (H4J00_01730) 387297..387695 - 399 Protein_331 hypothetical protein -
H4J00_RS01740 387687..387905 - 219 Protein_332 hypothetical protein -
H4J00_RS01745 (H4J00_01735) 388227..389150 + 924 WP_014505030.1 arginase -
H4J00_RS01750 (H4J00_01740) 389258..389410 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
H4J00_RS01755 (H4J00_01745) 389485..389619 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
H4J00_RS01760 (H4J00_01750) 389862..390072 + 211 Protein_336 CsbD family protein -
H4J00_RS01765 (H4J00_01755) 390241..391530 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
H4J00_RS01770 (H4J00_01760) 391661..392605 + 945 WP_044749698.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169061 WP_011257368.1 NZ_CP059710:389485-389619 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169061 NZ_CP076274:c2316581-2316327 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169061 WP_011407410.1 NZ_CP059710:389258-389410 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169061 NZ_CP076274:c2316829-2316578 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References