Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 430002..430352 Replicon chromosome
Accession NZ_CP059591
Organism Xanthomonas oryzae pv. oryzae strain IXO221

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO221_RS02025 Protein ID WP_011257368.1
Coordinates 430218..430352 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO221_RS02020 Protein ID WP_011407410.1
Coordinates 430002..430154 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO221_RS01995 (IXO221_002000) 426273..426956 - 684 WP_011257363.1 dTMP kinase -
IXO221_RS02000 427436..427978 - 543 Protein_383 GTPase -
IXO221_RS02005 (IXO221_002015) 427975..428439 - 465 Protein_384 hypothetical protein -
IXO221_RS02010 428431..428649 - 219 Protein_385 hypothetical protein -
IXO221_RS02015 (IXO221_002020) 428971..429894 + 924 WP_011407409.1 arginase -
IXO221_RS02020 (IXO221_002025) 430002..430154 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO221_RS02025 (IXO221_002030) 430218..430352 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO221_RS02030 (IXO221_002035) 430596..430805 + 210 WP_011407411.1 CsbD family protein -
IXO221_RS02035 (IXO221_002040) 430974..432263 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO221_RS02040 (IXO221_002045) 432394..433338 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169046 WP_011257368.1 NZ_CP059591:430218-430352 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169046 NZ_CP076272:4678086-4678259 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169046 WP_011407410.1 NZ_CP059591:430002-430154 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169046 NZ_CP076272:4677762-4678058 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References