Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 4680315..4680871 | Replicon | chromosome |
| Accession | NZ_CP059590 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO685 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | IXO685_RS21915 | Protein ID | WP_229002778.1 |
| Coordinates | 4680620..4680871 (+) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A854CIX2 |
| Locus tag | IXO685_RS21910 | Protein ID | WP_011408759.1 |
| Coordinates | 4680315..4680593 (+) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO685_RS21890 (IXO685_0021835) | 4675432..4675989 | - | 558 | WP_011259349.1 | DNA-3-methyladenine glycosylase | - |
| IXO685_RS21895 (IXO685_0021840) | 4676139..4677104 | - | 966 | WP_109181928.1 | IS1595-like element ISXo5 family transposase | - |
| IXO685_RS21900 (IXO685_0021845) | 4677685..4678869 | + | 1185 | WP_011408397.1 | IS256-like element IS1113 family transposase | - |
| IXO685_RS21905 (IXO685_0021855) | 4679733..4680119 | + | 387 | WP_205421001.1 | hypothetical protein | - |
| IXO685_RS21910 (IXO685_0021860) | 4680315..4680593 | + | 279 | WP_011408759.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| IXO685_RS21915 (IXO685_0021865) | 4680620..4680871 | + | 252 | WP_229002778.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| IXO685_RS21920 (IXO685_0021870) | 4680948..4681202 | + | 255 | WP_198912806.1 | hypothetical protein | - |
| IXO685_RS21925 | 4681195..4681329 | + | 135 | WP_011051575.1 | hypothetical protein | - |
| IXO685_RS21930 (IXO685_0021875) | 4681398..4681652 | + | 255 | WP_223293127.1 | hypothetical protein | - |
| IXO685_RS21935 | 4681869..4681988 | + | 120 | Protein_4200 | IS3 family transposase | - |
| IXO685_RS21940 (IXO685_0021880) | 4681957..4682085 | + | 129 | WP_012444694.1 | hypothetical protein | - |
| IXO685_RS21945 (IXO685_0021885) | 4682154..4682952 | + | 799 | WP_094187731.1 | IS5 family transposase | - |
| IXO685_RS21955 (IXO685_0021895) | 4683368..4683769 | - | 402 | WP_011259345.1 | H-NS family nucleoid-associated regulatory protein | - |
| IXO685_RS21960 (IXO685_0021900) | 4683991..4684167 | + | 177 | Protein_4204 | DUF3606 domain-containing protein | - |
| IXO685_RS21965 (IXO685_0021910) | 4684449..4684765 | + | 317 | Protein_4205 | ATP-dependent DNA ligase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 4676139..4682952 | 6813 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9617.95 Da Isoelectric Point: 9.9718
>T169045 WP_229002778.1 NZ_CP059590:4680620-4680871 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
Download Length: 252 bp
>T169045 NZ_CP076272:4399868-4400179 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTATTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTATTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10826.11 Da Isoelectric Point: 4.9736
>AT169045 WP_011408759.1 NZ_CP059590:4680315-4680593 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
Download Length: 279 bp
>AT169045 NZ_CP076272:4400180-4400470 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|