169044

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2733210..2733560 Replicon chromosome
Accession NZ_CP059590
Organism Xanthomonas oryzae pv. oryzae strain IXO685

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO685_RS12955 Protein ID WP_011257368.1
Coordinates 2733426..2733560 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO685_RS12950 Protein ID WP_011407410.1
Coordinates 2733210..2733362 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO685_RS12925 (IXO685_0012920) 2729481..2730164 - 684 WP_011257363.1 dTMP kinase -
IXO685_RS12930 2730644..2731186 - 543 Protein_2473 GTPase -
IXO685_RS12935 (IXO685_0012935) 2731183..2731647 - 465 Protein_2474 hypothetical protein -
IXO685_RS12940 2731639..2731857 - 219 Protein_2475 hypothetical protein -
IXO685_RS12945 (IXO685_0012940) 2732179..2733102 + 924 WP_011407409.1 arginase -
IXO685_RS12950 (IXO685_0012945) 2733210..2733362 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO685_RS12955 (IXO685_0012950) 2733426..2733560 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO685_RS12960 (IXO685_0012955) 2733804..2734013 + 210 WP_011407411.1 CsbD family protein -
IXO685_RS12965 (IXO685_0012960) 2734182..2735471 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO685_RS12970 (IXO685_0012965) 2735602..2736546 + 945 WP_080493520.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169044 WP_011257368.1 NZ_CP059590:2733426-2733560 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169044 NZ_CP076272:c3934313-3934083 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169044 WP_011407410.1 NZ_CP059590:2733210-2733362 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169044 NZ_CP076272:c3934086-3933727 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References