Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 664961..666480 Replicon chromosome
Accession NZ_CP059590
Organism Xanthomonas oryzae pv. oryzae strain IXO685

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO685_RS03015 Protein ID WP_011259680.1
Coordinates 664961..665884 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0K0GMG7
Locus tag IXO685_RS03020 Protein ID WP_012445456.1
Coordinates 665881..666480 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO685_RS02980 (IXO685_0003035) 660560..660712 + 153 Protein_572 SAM-dependent methyltransferase -
IXO685_RS02985 (IXO685_0003040) 660824..662200 + 1377 WP_133264775.1 IS5 family transposase -
IXO685_RS02990 (IXO685_0003045) 662220..662752 + 533 Protein_574 protein N-lysine methyltransferase family protein -
IXO685_RS02995 (IXO685_0003050) 662769..663278 - 510 WP_011259678.1 hypothetical protein -
IXO685_RS03000 (IXO685_0003055) 663703..663945 - 243 WP_011259679.1 hypothetical protein -
IXO685_RS03005 (IXO685_0003060) 663942..664427 - 486 WP_143681140.1 hypothetical protein -
IXO685_RS03010 664411..664881 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO685_RS03015 (IXO685_0003075) 664961..665884 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO685_RS03020 (IXO685_0003080) 665881..666480 - 600 WP_012445456.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO685_RS03025 (IXO685_0003085) 666845..667135 + 291 WP_229002604.1 FaeA/PapI family transcriptional regulator -
IXO685_RS03030 (IXO685_0003090) 667167..667655 + 489 WP_027703988.1 BrxE family protein -
IXO685_RS03035 (IXO685_0003095) 668169..668170 - 2 WP_094187708.1 IS5 family transposase -
IXO685_RS03040 (IXO685_0003100) 668576..669609 - 1034 Protein_584 IS630 family transposase -
IXO685_RS03045 670108..670398 + 291 WP_011409031.1 hypothetical protein -
IXO685_RS03050 670379..670753 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 660824..662200 1376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T169041 WP_011259680.1 NZ_CP059590:c665884-664961 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T169041 NZ_CP076272:c3343049-3342642 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22051.76 Da        Isoelectric Point: 10.1240

>AT169041 WP_012445456.1 NZ_CP059590:c666480-665881 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT169041 NZ_CP076272:c3343296-3343030 [Escherichia coli]
ATGGACATTAATAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A0K0GMG7

References